Cornejo A - Search Results

1

The Cytotoxic Effect of α-Synuclein Aggregates.

Melo F, Caballero L, Zamorano E, Ventura N, Navarro C, Doll I, Zamorano P, Cornejo A. Melo F, et al. Among authors: cornejo a. Chemphyschem. 2021 Mar 17;22(6):526-532. doi: 10.1002/cphc.202000831. Epub 2021 Feb 16. Chemphyschem. 2021. PMID: 33482036

2

Fulvic acid inhibits aggregation and promotes disassembly of tau fibrils associated with Alzheimer's disease.

Cornejo A, Jiménez JM, Caballero L, Melo F, Maccioni RB. Cornejo A, et al. J Alzheimers Dis. 2011;27(1):143-53. doi: 10.3233/JAD-2011-110623. J Alzheimers Dis. 2011. PMID: 21785188

3

Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer's disease.

Cornejo A, Aguilar Sandoval F, Caballero L, Machuca L, Muñoz P, Caballero J, Perry G, Ardiles A, Areche C, Melo F. Cornejo A, et al. J Enzyme Inhib Med Chem. 2017 Dec;32(1):945-953. doi: 10.1080/14756366.2017.1347783. J Enzyme Inhib Med Chem. 2017. PMID: 28701064 Free PMC article.

4

Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine-Cysteine Interaction.

Areche C, Zapata F, González M, Díaz E, Montecinos R, Hernández M, Melo F, Cornejo A. Areche C, et al. Among authors: cornejo a. ChemistryOpen. 2019 Feb 8;8(5):554-559. doi: 10.1002/open.201800222. eCollection 2019 May. ChemistryOpen. 2019. PMID: 31065505 Free PMC article.

5

Dammarane triterpenes targeting α-synuclein: biological activity and evaluation of binding sites by molecular docking.

Cornejo A, Caballero J, Simirgiotis M, Torres V, Sánchez L, Díaz N, Guimaraes M, Hernández M, Areche C, Alfaro S, Caballero L, Melo F. Cornejo A, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):154-162. doi: 10.1080/14756366.2020.1851216. J Enzyme Inhib Med Chem. 2021. PMID: 33307873 Free PMC article.

6

The Fumarprotocetraric Acid Inhibits Tau Covalently, Avoiding Cytotoxicity of Aggregates in Cells.

González C, Cartagena C, Caballero L, Melo F, Areche C, Cornejo A. González C, et al. Among authors: cornejo a. Molecules. 2021 Jun 21;26(12):3760. doi: 10.3390/molecules26123760. Molecules. 2021. PMID: 34205516 Free PMC article.

7

α-Synuclein Drives Tau's Cytotoxic Aggregates Formation through Hydrophobic Interactions.

Ojeda A, Cofré V, Melo F, Caballero L, Fuentealba D, Cornejo A. Ojeda A, et al. Among authors: cornejo a. Chempluschem. 2023 Oct;88(10):e202300257. doi: 10.1002/cplu.202300257. Epub 2023 Oct 4. Chempluschem. 2023. PMID: 37708459

8

Rosmarinic acid turned α-syn oligomers into non-toxic species preserving microtubules in Raw 264.7 cells.

Flores N, Rivillas-Acevedo L, Caballero J, Melo F, Caballero L, Areche C, Fuentealba D, Aguilar F, Cornejo A. Flores N, et al. Among authors: cornejo a. Bioorg Chem. 2024 Oct;151:107669. doi: 10.1016/j.bioorg.2024.107669. Epub 2024 Jul 23. Bioorg Chem. 2024. PMID: 39067421

9

Bringing the Spotlight to Tau and TDP-43 in Frontotemporal Dementia: A Review of Promising Chemical Compounds.

Villalobos-Nova K, Monroy-Moya S, Maulen-Peñaloza J, Pinto GCM, Cornejo A. Villalobos-Nova K, et al. Among authors: cornejo a. Curr Med Chem. 2022;29(38):5903-5924. doi: 10.2174/0929867329666220508175340. Curr Med Chem. 2022. PMID: 35532254 Review.

10

Mechanisms of tau self-aggregation and neurotoxicity.

Farías G, Cornejo A, Jiménez J, Guzmán L, Maccioni RB. Farías G, et al. Among authors: cornejo a. Curr Alzheimer Res. 2011 Sep;8(6):608-14. doi: 10.2174/156720511796717258. Curr Alzheimer Res. 2011. PMID: 21605046 Review.

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