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High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale.
Downes DJ, Beagrie RA, Gosden ME, Telenius J, Carpenter SJ, Nussbaum L, De Ornellas S, Sergeant M, Eijsbouts CQ, Schwessinger R, Kerry J, Roberts N, Shivalingam A, El-Sagheer A, Oudelaar AM, Brown T, Buckle VJ, Davies JOJ, Hughes JR. Downes DJ, et al. Among authors: hughes jr. Nat Commun. 2021 Jan 22;12(1):531. doi: 10.1038/s41467-020-20809-6. Nat Commun. 2021. PMID: 33483495 Free PMC article.
Intragenic enhancers act as alternative promoters.
Kowalczyk MS, Hughes JR, Garrick D, Lynch MD, Sharpe JA, Sloane-Stanley JA, McGowan SJ, De Gobbi M, Hosseini M, Vernimmen D, Brown JM, Gray NE, Collavin L, Gibbons RJ, Flint J, Taylor S, Buckle VJ, Milne TA, Wood WG, Higgs DR. Kowalczyk MS, et al. Among authors: hughes jr. Mol Cell. 2012 Feb 24;45(4):447-58. doi: 10.1016/j.molcel.2011.12.021. Epub 2012 Jan 19. Mol Cell. 2012. PMID: 22264824 Free article.
High-resolution analysis of cis-acting regulatory networks at the α-globin locus.
Hughes JR, Lower KM, Dunham I, Taylor S, De Gobbi M, Sloane-Stanley JA, McGowan S, Ragoussis J, Vernimmen D, Gibbons RJ, Higgs DR. Hughes JR, et al. Philos Trans R Soc Lond B Biol Sci. 2013 May 6;368(1620):20120361. doi: 10.1098/rstb.2012.0361. Print 2013. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 23650635 Free PMC article.
Unlinking an lncRNA from Its Associated cis Element.
Paralkar VR, Taborda CC, Huang P, Yao Y, Kossenkov AV, Prasad R, Luan J, Davies JO, Hughes JR, Hardison RC, Blobel GA, Weiss MJ. Paralkar VR, et al. Among authors: hughes jr. Mol Cell. 2016 Apr 7;62(1):104-10. doi: 10.1016/j.molcel.2016.02.029. Epub 2016 Mar 31. Mol Cell. 2016. PMID: 27041223 Free PMC article.
1,226 results