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Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness.
Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, Wu JC, Moon RT, Si Dong PD, Karakikes I, Cashman JR, Mercola M. Cheng J, et al. Among authors: perea gil i. Cell Chem Biol. 2021 May 20;28(5):625-635.e5. doi: 10.1016/j.chembiol.2021.01.001. Epub 2021 Jan 26. Cell Chem Biol. 2021. PMID: 33503403 Free PMC article.
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
Perea-Gil I, Seeger T, Bruyneel AAN, Termglinchan V, Monte E, Lim EW, Vadgama N, Furihata T, Gavidia AA, Arthur Ataam J, Bharucha N, Martinez-Amador N, Ameen M, Nair P, Serrano R, Kaur B, Feyen DAM, Diecke S, Snyder MP, Metallo CM, Mercola M, Karakikes I. Perea-Gil I, et al. Eur Heart J. 2022 Sep 21;43(36):3477-3489. doi: 10.1093/eurheartj/ehac305. Eur Heart J. 2022. PMID: 35728000 Free PMC article.
Unfolded Protein Response as a Compensatory Mechanism and Potential Therapeutic Target in PLN R14del Cardiomyopathy.
Feyen DAM, Perea-Gil I, Maas RGC, Harakalova M, Gavidia AA, Arthur Ataam J, Wu TH, Vink A, Pei J, Vadgama N, Suurmeijer AJ, Te Rijdt WP, Vu M, Amatya PL, Prado M, Zhang Y, Dunkenberger L, Sluijter JPG, Sallam K, Asselbergs FW, Mercola M, Karakikes I. Feyen DAM, et al. Among authors: perea gil i. Circulation. 2021 Aug 3;144(5):382-392. doi: 10.1161/CIRCULATIONAHA.120.049844. Epub 2021 Apr 30. Circulation. 2021. PMID: 33928785 Free PMC article.
A Novel Recessive Mutation in SPEG Causes Early Onset Dilated Cardiomyopathy.
Levitas A, Muhammad E, Zhang Y, Perea Gil I, Serrano R, Diaz N, Arafat M, Gavidia AA, Kapiloff MS, Mercola M, Etzion Y, Parvari R, Karakikes I. Levitas A, et al. Among authors: perea gil i. PLoS Genet. 2020 Sep 14;16(9):e1009000. doi: 10.1371/journal.pgen.1009000. eCollection 2020 Sep. PLoS Genet. 2020. PMID: 32925938 Free PMC article.
Noninvasive Assessment of an Engineered Bioactive Graft in Myocardial Infarction: Impact on Cardiac Function and Scar Healing.
Gálvez-Montón C, Bragós R, Soler-Botija C, Díaz-Güemes I, Prat-Vidal C, Crisóstomo V, Sánchez-Margallo FM, Llucià-Valldeperas A, Bogónez-Franco P, Perea-Gil I, Roura S, Bayes-Genis A. Gálvez-Montón C, et al. Stem Cells Transl Med. 2017 Feb;6(2):647-655. doi: 10.5966/sctm.2016-0063. Epub 2016 Sep 2. Stem Cells Transl Med. 2017. PMID: 28191775 Free PMC article.
Preclinical Safety Evaluation of Allogeneic Induced Pluripotent Stem Cell-Based Therapy in a Swine Model of Myocardial Infarction.
Gálvez-Montón C, Soler-Botija C, Iborra-Egea O, Díaz-Güemes I, Martí M, Iglesias-García O, Prat-Vidal C, Crisóstomo V, Llucià-Valldeperas A, Perea-Gil I, Roura S, Sánchez-Margallo FM, Raya Á, Bayes-Genis A. Gálvez-Montón C, et al. Tissue Eng Part C Methods. 2017 Nov;23(11):736-744. doi: 10.1089/ten.TEC.2017.0156. Epub 2017 Aug 18. Tissue Eng Part C Methods. 2017. PMID: 28699384
Electromechanical Conditioning of Adult Progenitor Cells Improves Recovery of Cardiac Function After Myocardial Infarction.
Llucià-Valldeperas A, Soler-Botija C, Gálvez-Montón C, Roura S, Prat-Vidal C, Perea-Gil I, Sanchez B, Bragos R, Vunjak-Novakovic G, Bayes-Genis A. Llucià-Valldeperas A, et al. Stem Cells Transl Med. 2017 Mar;6(3):970-981. doi: 10.5966/sctm.2016-0079. Epub 2016 Sep 29. Stem Cells Transl Med. 2017. PMID: 28297585 Free PMC article.
27 results