Soave M - Search Results

1

Detection of genome-edited and endogenously expressed G protein-coupled receptors.

Soave M, Stoddart LA, White CW, Kilpatrick LE, Goulding J, Briddon SJ, Hill SJ. Soave M, et al. FEBS J. 2021 Apr;288(8):2585-2601. doi: 10.1111/febs.15729. Epub 2021 Feb 9. FEBS J. 2021. PMID: 33506623 Free PMC article. Review.

2

Use of a new proximity assay (NanoBRET) to investigate the ligand-binding characteristics of three fluorescent ligands to the human β₁-adrenoceptor expressed in HEK-293 cells.

Soave M, Stoddart LA, Brown A, Woolard J, Hill SJ. Soave M, et al. Pharmacol Res Perspect. 2016 Aug 8;4(5):e00250. doi: 10.1002/prp2.250. eCollection 2016 Oct. Pharmacol Res Perspect. 2016. PMID: 27588207 Free PMC article.

3

A monoclonal antibody raised against a thermo-stabilised β₁-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β₁-adrenoceptors expressed in stable cell lines.

Soave M, Cseke G, Hutchings CJ, Brown AJH, Woolard J, Hill SJ. Soave M, et al. Biochem Pharmacol. 2018 Jan;147:38-54. doi: 10.1016/j.bcp.2017.10.015. Epub 2017 Nov 2. Biochem Pharmacol. 2018. PMID: 29102678 Free PMC article.

4

Probe dependence of allosteric enhancers on the binding affinity of adenosine A₁ -receptor agonists at rat and human A₁ -receptors measured using NanoBRET.

Cooper SL, Soave M, Jörg M, Scammells PJ, Woolard J, Hill SJ. Cooper SL, et al. Among authors: soave m. Br J Pharmacol. 2019 Apr;176(7):864-878. doi: 10.1111/bph.14575. Epub 2019 Mar 6. Br J Pharmacol. 2019. PMID: 30644086 Free PMC article.

5

NanoBiT Complementation to Monitor Agonist-Induced Adenosine A₁ Receptor Internalization.

Soave M, Kellam B, Woolard J, Briddon SJ, Hill SJ. Soave M, et al. SLAS Discov. 2020 Feb;25(2):186-194. doi: 10.1177/2472555219880475. Epub 2019 Oct 4. SLAS Discov. 2020. PMID: 31583945 Free PMC article.

6

Application of Fluorescent Purinoceptor Antagonists for Bioluminescence Resonance Energy Transfer Assays and Fluorescent Microscopy.

Soave M, Goulding J, Markus R, Hill SJ, Stoddart LA. Soave M, et al. Methods Mol Biol. 2020;2041:163-181. doi: 10.1007/978-1-4939-9717-6_12. Methods Mol Biol. 2020. PMID: 31646488

7

Fluorescent ligands: Bringing light to emerging GPCR paradigms.

Soave M, Briddon SJ, Hill SJ, Stoddart LA. Soave M, et al. Br J Pharmacol. 2020 Mar;177(5):978-991. doi: 10.1111/bph.14953. Epub 2020 Feb 6. Br J Pharmacol. 2020. PMID: 31877233 Free PMC article. Review.

8

Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A_2A Receptor.

Comeo E, Kindon ND, Soave M, Stoddart LA, Kilpatrick LE, Scammells PJ, Hill SJ, Kellam B. Comeo E, et al. Among authors: soave m. J Med Chem. 2020 Mar 12;63(5):2656-2672. doi: 10.1021/acs.jmedchem.9b01856. Epub 2020 Jan 9. J Med Chem. 2020. PMID: 31887252 Free article.

9

Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies.

Soave M, Heukers R, Kellam B, Woolard J, Smit MJ, Briddon SJ, Hill SJ. Soave M, et al. Cell Chem Biol. 2020 Oct 15;27(10):1250-1261.e5. doi: 10.1016/j.chembiol.2020.06.006. Epub 2020 Jun 30. Cell Chem Biol. 2020. PMID: 32610042 Free PMC article.

10

Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.

Clark JC, Neagoe RAI, Zuidscherwoude M, Kavanagh DM, Slater A, Martin EM, Soave M, Stegner D, Nieswandt B, Poulter NS, Hummert J, Herten DP, Tomlinson MG, Hill SJ, Watson SP. Clark JC, et al. Among authors: soave m. Thromb Haemost. 2021 Nov;121(11):1435-1447. doi: 10.1055/a-1401-5014. Epub 2021 Apr 14. Thromb Haemost. 2021. PMID: 33638140

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