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Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant.
Annunziato G, Spadini C, Franko N, Storici P, Demitri N, Pieroni M, Flisi S, Rosati L, Iannarelli M, Marchetti M, Magalhaes J, Bettati S, Mozzarelli A, Cabassi CS, Campanini B, Costantino G. Annunziato G, et al. Among authors: magalhaes j. ACS Infect Dis. 2021 Feb 12;7(2):281-292. doi: 10.1021/acsinfecdis.0c00378. Epub 2021 Jan 29. ACS Infect Dis. 2021. PMID: 33513010
Refining the structure-activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms.
Magalhães J, Franko N, Annunziato G, Pieroni M, Benoni R, Nikitjuka A, Mozzarelli A, Bettati S, Karawajczyk A, Jirgensons A, Campanini B, Costantino G. Magalhães J, et al. J Enzyme Inhib Med Chem. 2019 Dec;34(1):31-43. doi: 10.1080/14756366.2018.1518959. J Enzyme Inhib Med Chem. 2019. PMID: 30362368 Free PMC article.
Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR.
Annunziato G, Pieroni M, Benoni R, Campanini B, Pertinhez TA, Pecchini C, Bruno A, Magalhães J, Bettati S, Franko N, Mozzarelli A, Costantino G. Annunziato G, et al. Among authors: magalhaes j. J Enzyme Inhib Med Chem. 2016;31(sup4):78-87. doi: 10.1080/14756366.2016.1218486. Epub 2016 Aug 31. J Enzyme Inhib Med Chem. 2016. PMID: 27578398 Free article.
Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants.
Magalhães J, Franko N, Raboni S, Annunziato G, Tammela P, Bruno A, Bettati S, Armao S, Spadini C, Cabassi CS, Mozzarelli A, Pieroni M, Campanini B, Costantino G. Magalhães J, et al. Pharmaceuticals (Basel). 2021 Feb 23;14(2):174. doi: 10.3390/ph14020174. Pharmaceuticals (Basel). 2021. PMID: 33672408 Free PMC article.
From hybrid compounds to targeted drug delivery in antimalarial therapy.
Oliveira R, Miranda D, Magalhães J, Capela R, Perry MJ, O'Neill PM, Moreira R, Lopes F. Oliveira R, et al. Among authors: magalhaes j. Bioorg Med Chem. 2015 Aug 15;23(16):5120-30. doi: 10.1016/j.bmc.2015.04.017. Epub 2015 Apr 11. Bioorg Med Chem. 2015. PMID: 25913864 Review.
983 results