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Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease.
Khadhraoui N, Prola A, Vandestienne A, Blondelle J, Guillaud L, Courtin G, Bodak M, Prost B, Huet H, Wintrebert M, Péchoux C, Solgadi A, Relaix F, Tiret L, Pilot-Storck F. Khadhraoui N, et al. Mol Metab. 2023 Mar;69:101677. doi: 10.1016/j.molmet.2023.101677. Epub 2023 Jan 21. Mol Metab. 2023. PMID: 36693621 Free PMC article.
Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle.
Prola A, Blondelle J, Vandestienne A, Piquereau J, Denis RGP, Guyot S, Chauvin H, Mourier A, Maurer M, Henry C, Khadhraoui N, Gallerne C, Molinié T, Courtin G, Guillaud L, Gressette M, Solgadi A, Dumont F, Castel J, Ternacle J, Demarquoy J, Malgoyre A, Koulmann N, Derumeaux G, Giraud MF, Joubert F, Veksler V, Luquet S, Relaix F, Tiret L, Pilot-Storck F. Prola A, et al. Among authors: khadhraoui n. Sci Adv. 2021 Jan 1;7(1):eabd6322. doi: 10.1126/sciadv.abd6322. Print 2021 Jan. Sci Adv. 2021. PMID: 33523852 Free PMC article.