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Page 1
Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor.
Wei X, Qu B, Zeng X, Savoie J, Fandrick KR, Desrosiers JN, Tcyrulnikov S, Marsini MA, Buono FG, Li Z, Yang BS, Tang W, Haddad N, Gutierrez O, Wang J, Lee H, Ma S, Campbell S, Lorenz JC, Eckhardt M, Himmelsbach F, Peters S, Patel ND, Tan Z, Yee NK, Song JJ, Roschangar F, Kozlowski MC, Senanayake CH. Wei X, et al. Among authors: kozlowski mc. J Am Chem Soc. 2016 Nov 30;138(47):15473-15481. doi: 10.1021/jacs.6b09764. Epub 2016 Nov 17. J Am Chem Soc. 2016. PMID: 27794616 Free PMC article.
Enantioselective Nickel-Catalyzed Mizoroki-Heck Cyclizations To Generate Quaternary Stereocenters.
Desrosiers JN, Wen J, Tcyrulnikov S, Biswas S, Qu B, Hie L, Kurouski D, Wu L, Grinberg N, Haddad N, Busacca CA, Yee NK, Song JJ, Garg NK, Zhang X, Kozlowski MC, Senanayake CH. Desrosiers JN, et al. Among authors: kozlowski mc. Org Lett. 2017 Jul 7;19(13):3338-3341. doi: 10.1021/acs.orglett.7b01054. Epub 2017 Jun 12. Org Lett. 2017. PMID: 28604006 Free PMC article.
Enantioselective Synthesis of α-(Hetero)aryl Piperidines through Asymmetric Hydrogenation of Pyridinium Salts and Its Mechanistic Insights.
Qu B, Mangunuru HPR, Tcyrulnikov S, Rivalti D, Zatolochnaya OV, Kurouski D, Radomkit S, Biswas S, Karyakarte S, Fandrick KR, Sieber JD, Rodriguez S, Desrosiers JN, Haddad N, McKellop K, Pennino S, Lee H, Yee NK, Song JJ, Kozlowski MC, Senanayake CH. Qu B, et al. Among authors: kozlowski mc. Org Lett. 2018 Mar 2;20(5):1333-1337. doi: 10.1021/acs.orglett.8b00067. Epub 2018 Feb 20. Org Lett. 2018. PMID: 29461064 Free PMC article.
Copper-catalyzed asymmetric hydrogenation of 2-substituted ketones via dynamic kinetic resolution.
Zatolochnaya OV, Rodríguez S, Zhang Y, Lao KS, Tcyrulnikov S, Li G, Wang XJ, Qu B, Biswas S, Mangunuru HPR, Rivalti D, Sieber JD, Desrosiers JN, Leung JC, Grinberg N, Lee H, Haddad N, Yee NK, Song JJ, Kozlowski MC, Senanayake CH. Zatolochnaya OV, et al. Among authors: kozlowski mc. Chem Sci. 2018 Apr 23;9(19):4505-4510. doi: 10.1039/c8sc00434j. eCollection 2018 May 21. Chem Sci. 2018. PMID: 29896393 Free PMC article.
Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho-Substituted Biaryl Synthesis.
Patel ND, Sieber JD, Tcyrulnikov S, Simmons BJ, Rivalti D, Duvvuri K, Zhang Y, Gao DA, Fandrick KR, Haddad N, Lao KS, Mangunuru HPR, Biswas S, Qu B, Grinberg N, Pennino S, Lee H, Song JJ, Gupton BF, Garg NK, Kozlowski MC, Senanayake CH. Patel ND, et al. Among authors: kozlowski mc. ACS Catal. 2018 Nov 2;8(11):10190-10209. doi: 10.1021/acscatal.8b02509. Epub 2018 Sep 20. ACS Catal. 2018. PMID: 30450265 Free PMC article.
A versatile catalyst system for enantioselective synthesis of 2-substituted 1,4-benzodioxanes.
Chong E, Qu B, Zhang Y, Cannone ZP, Leung JC, Tcyrulnikov S, Nguyen KD, Haddad N, Biswas S, Hou X, Kaczanowska K, Chwalba M, Tracz A, Czarnocki S, Song JJ, Kozlowski MC, Senanayake CH. Chong E, et al. Among authors: kozlowski mc. Chem Sci. 2019 Mar 13;10(15):4339-4345. doi: 10.1039/c8sc05612a. eCollection 2019 Apr 21. Chem Sci. 2019. PMID: 31057761 Free PMC article.
178 results