Mott BT - Search Results

1

Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax.

Moses BS, McCullough S, Fox JM, Mott BT, Bentzen SM, Kim M, Tyner JW, Lapidus RG, Emadi A, Rudek MA, Kingsbury TJ, Civin CI. Moses BS, et al. Among authors: mott bt. Blood Adv. 2021 Feb 9;5(3):711-724. doi: 10.1182/bloodadvances.2020003429. Blood Adv. 2021. PMID: 33560385 Free PMC article.

2

An artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activities.

He R, Mott BT, Rosenthal AS, Genna DT, Posner GH, Arav-Boger R. He R, et al. Among authors: mott bt. PLoS One. 2011;6(8):e24334. doi: 10.1371/journal.pone.0024334. Epub 2011 Aug 31. PLoS One. 2011. PMID: 21904628 Free PMC article.

3

Artemisinin-derived dimer phosphate esters as potent anti-cytomegalovirus (anti-CMV) and anti-cancer agents: a structure-activity study.

Mott BT, He R, Chen X, Fox JM, Civin CI, Arav-Boger R, Posner GH. Mott BT, et al. Bioorg Med Chem. 2013 Jul 1;21(13):3702-7. doi: 10.1016/j.bmc.2013.04.027. Epub 2013 Apr 22. Bioorg Med Chem. 2013. PMID: 23673218 Free PMC article.

4

Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs.

Fox JM, Moynihan JR, Mott BT, Mazzone JR, Anders NM, Brown PA, Rudek MA, Liu JO, Arav-Boger R, Posner GH, Civin CI, Chen X. Fox JM, et al. Among authors: mott bt. Oncotarget. 2016 Feb 9;7(6):7268-79. doi: 10.18632/oncotarget.6896. Oncotarget. 2016. PMID: 26771236 Free PMC article.

5

A Novel 2-Carbon-Linked Dimeric Artemisinin With Potent Antileukemic Activity and Favorable Pharmacology.

Kagan AB, Moses BS, Mott BT, Rai G, Anders NM, Rudek MA, Civin CI. Kagan AB, et al. Among authors: mott bt. Front Oncol. 2022 Jan 11;11:790037. doi: 10.3389/fonc.2021.790037. eCollection 2021. Front Oncol. 2022. PMID: 35127495 Free PMC article.

6

ART714 is a best-in-class antileukemic 2-carbon-linked dimeric artemisinin derivative.

Kagan AB, Moses BS, Lapidus R, Mott BT, Rai G, Anders NM, Hoag SW, Rudek MA, Civin CI. Kagan AB, et al. Among authors: mott bt. Cancer Chemother Pharmacol. 2023 Jul;92(1):39-50. doi: 10.1007/s00280-023-04539-2. Epub 2023 May 30. Cancer Chemother Pharmacol. 2023. PMID: 37249624

7

Artemisinin-derived dimer diphenyl phosphate is an irreversible inhibitor of human cytomegalovirus replication.

He R, Park K, Cai H, Kapoor A, Forman M, Mott B, Posner GH, Arav-Boger R. He R, et al. Antimicrob Agents Chemother. 2012 Jul;56(7):3508-15. doi: 10.1128/AAC.00519-12. Epub 2012 Apr 30. Antimicrob Agents Chemother. 2012. PMID: 22547612 Free PMC article.

8

Unique and highly selective anticytomegalovirus activities of artemisinin-derived dimer diphenyl phosphate stem from combination of dimer unit and a diphenyl phosphate moiety.

He R, Forman M, Mott BT, Venkatadri R, Posner GH, Arav-Boger R. He R, et al. Among authors: mott bt. Antimicrob Agents Chemother. 2013 Sep;57(9):4208-14. doi: 10.1128/AAC.00893-13. Epub 2013 Jun 17. Antimicrob Agents Chemother. 2013. PMID: 23774439 Free PMC article.

9

Thiazole, oxadiazole, and carboxamide derivatives of artemisinin are highly selective and potent inhibitors of Toxoplasma gondii.

Hencken CP, Jones-Brando L, Bordón C, Stohler R, Mott BT, Yolken R, Posner GH, Woodard LE. Hencken CP, et al. Among authors: mott bt. J Med Chem. 2010 May 13;53(9):3594-601. doi: 10.1021/jm901857d. J Med Chem. 2010. PMID: 20373807 Free PMC article.

10

Synthesis and antimalarial efficacy of two-carbon-linked, artemisinin-derived trioxane dimers in combination with known antimalarial drugs.

Mott BT, Tripathi A, Siegler MA, Moore CD, Sullivan DJ, Posner GH. Mott BT, et al. J Med Chem. 2013 Mar 28;56(6):2630-41. doi: 10.1021/jm400058j. Epub 2013 Mar 7. J Med Chem. 2013. PMID: 23425037 Free PMC article.

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