Elledge SJ - Search Results

1

Systematic characterization of mutations altering protein degradation in human cancers.

Tokheim C, Wang X, Timms RT, Zhang B, Mena EL, Wang B, Chen C, Ge J, Chu J, Zhang W, Elledge SJ, Brown M, Liu XS. Tokheim C, et al. Among authors: elledge sj. Mol Cell. 2021 Mar 18;81(6):1292-1308.e11. doi: 10.1016/j.molcel.2021.01.020. Epub 2021 Feb 9. Mol Cell. 2021. PMID: 33567269 Free PMC article.

2

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.

Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER 3rd, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ. Smogorzewska A, et al. Among authors: elledge sj. Cell. 2007 Apr 20;129(2):289-301. doi: 10.1016/j.cell.2007.03.009. Epub 2007 Apr 5. Cell. 2007. PMID: 17412408 Free PMC article.

3

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ. Luo J, et al. Among authors: elledge sj. Cell. 2009 May 29;137(5):835-48. doi: 10.1016/j.cell.2009.05.006. Cell. 2009. PMID: 19490893 Free PMC article.

4

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.

O'Connell BC, Adamson B, Lydeard JR, Sowa ME, Ciccia A, Bredemeyer AL, Schlabach M, Gygi SP, Elledge SJ, Harper JW. O'Connell BC, et al. Among authors: elledge sj. Mol Cell. 2010 Nov 24;40(4):645-57. doi: 10.1016/j.molcel.2010.10.022. Epub 2010 Nov 4. Mol Cell. 2010. PMID: 21055985 Free PMC article.

5

Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress.

Ciccia A, Nimonkar AV, Hu Y, Hajdu I, Achar YJ, Izhar L, Petit SA, Adamson B, Yoon JC, Kowalczykowski SC, Livingston DM, Haracska L, Elledge SJ. Ciccia A, et al. Among authors: elledge sj. Mol Cell. 2012 Aug 10;47(3):396-409. doi: 10.1016/j.molcel.2012.05.024. Epub 2012 Jun 14. Mol Cell. 2012. PMID: 22704558 Free PMC article.

6

Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome.

Davoli T, Xu AW, Mengwasser KE, Sack LM, Yoon JC, Park PJ, Elledge SJ. Davoli T, et al. Among authors: elledge sj. Cell. 2013 Nov 7;155(4):948-62. doi: 10.1016/j.cell.2013.10.011. Epub 2013 Oct 31. Cell. 2013. PMID: 24183448 Free PMC article.

7

RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks.

Elia AE, Wang DC, Willis NA, Boardman AP, Hajdu I, Adeyemi RO, Lowry E, Gygi SP, Scully R, Elledge SJ. Elia AE, et al. Among authors: elledge sj. Mol Cell. 2015 Oct 15;60(2):280-93. doi: 10.1016/j.molcel.2015.09.011. Mol Cell. 2015. PMID: 26474068 Free PMC article.

8

Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.

Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ. Davoli T, et al. Among authors: elledge sj. Genes Dev. 2016 Dec 15;30(24):2684-2695. doi: 10.1101/gad.290122.116. Genes Dev. 2016. PMID: 28087713 Free PMC article.

9

A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.

Martin TD, Cook DR, Choi MY, Li MZ, Haigis KM, Elledge SJ. Martin TD, et al. Among authors: elledge sj. Cell Rep. 2017 Jul 11;20(2):427-438. doi: 10.1016/j.celrep.2017.06.061. Cell Rep. 2017. PMID: 28700943 Free PMC article.

10

C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases.

Lin HC, Yeh CW, Chen YF, Lee TT, Hsieh PY, Rusnac DV, Lin SY, Elledge SJ, Zheng N, Yen HS. Lin HC, et al. Among authors: elledge sj. Mol Cell. 2018 May 17;70(4):602-613.e3. doi: 10.1016/j.molcel.2018.04.006. Mol Cell. 2018. PMID: 29775578 Free PMC article.

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