Cox RD - Search Results

1

The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion.

Sachse G, Haythorne E, Hill T, Proks P, Joynson R, Terrón-Expósito R, Bentley L, Tucker SJ, Cox RD, Ashcroft FM. Sachse G, et al. Among authors: cox rd. Diabetes. 2021 May;70(5):1145-1156. doi: 10.2337/db20-0691. Epub 2021 Feb 10. Diabetes. 2021. PMID: 33568422

2

A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.

Toye AA, Moir L, Hugill A, Bentley L, Quarterman J, Mijat V, Hough T, Goldsworthy M, Haynes A, Hunter AJ, Browne M, Spurr N, Cox RD. Toye AA, et al. Among authors: cox rd. Diabetes. 2004 Jun;53(6):1577-83. doi: 10.2337/diabetes.53.6.1577. Diabetes. 2004. PMID: 15161764

3

A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.

Toye AA, Lippiat JD, Proks P, Shimomura K, Bentley L, Hugill A, Mijat V, Goldsworthy M, Moir L, Haynes A, Quarterman J, Freeman HC, Ashcroft FM, Cox RD. Toye AA, et al. Among authors: cox rd. Diabetologia. 2005 Apr;48(4):675-86. doi: 10.1007/s00125-005-1680-z. Epub 2005 Feb 24. Diabetologia. 2005. PMID: 15729571 Free article.

4

Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.

Freeman H, Shimomura K, Horner E, Cox RD, Ashcroft FM. Freeman H, et al. Among authors: cox rd. Cell Metab. 2006 Jan;3(1):35-45. doi: 10.1016/j.cmet.2005.10.008. Cell Metab. 2006. PMID: 16399503 Free article.

5

Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice.

Freeman HC, Hugill A, Dear NT, Ashcroft FM, Cox RD. Freeman HC, et al. Among authors: cox rd. Diabetes. 2006 Jul;55(7):2153-6. doi: 10.2337/db06-0358. Diabetes. 2006. PMID: 16804088

6

Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.

Freeman H, Shimomura K, Cox RD, Ashcroft FM. Freeman H, et al. Among authors: cox rd. Biochem Soc Trans. 2006 Nov;34(Pt 5):806-10. doi: 10.1042/BST0340806. Biochem Soc Trans. 2006. PMID: 17052203

7

R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion.

Zhang Q, Bengtsson M, Partridge C, Salehi A, Braun M, Cox R, Eliasson L, Johnson PR, Renström E, Schneider T, Berggren PO, Göpel S, Ashcroft FM, Rorsman P. Zhang Q, et al. Nat Cell Biol. 2007 Apr;9(4):453-60. doi: 10.1038/ncb1563. Epub 2007 Mar 18. Nat Cell Biol. 2007. PMID: 17369816

8

A kinetic core model of the glucose-stimulated insulin secretion network of pancreatic beta cells.

Jiang N, Cox RD, Hancock JM. Jiang N, et al. Among authors: cox rd. Mamm Genome. 2007 Jul;18(6-7):508-20. doi: 10.1007/s00335-007-9011-y. Epub 2007 May 21. Mamm Genome. 2007. PMID: 17514510 Free PMC article.

9

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.

Goldsworthy M, Hugill A, Freeman H, Horner E, Shimomura K, Bogani D, Pieles G, Mijat V, Arkell R, Bhattacharya S, Ashcroft FM, Cox RD. Goldsworthy M, et al. Among authors: cox rd. Diabetes. 2008 Aug;57(8):2234-44. doi: 10.2337/db07-0337. Epub 2008 May 13. Diabetes. 2008. PMID: 18477811 Free PMC article.

10

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.

Girard CA, Wunderlich FT, Shimomura K, Collins S, Kaizik S, Proks P, Abdulkader F, Clark A, Ball V, Zubcevic L, Bentley L, Clark R, Church C, Hugill A, Galvanovskis J, Cox R, Rorsman P, Brüning JC, Ashcroft FM. Girard CA, et al. J Clin Invest. 2009 Jan;119(1):80-90. doi: 10.1172/JCI35772. Epub 2008 Dec 8. J Clin Invest. 2009. PMID: 19065048 Free PMC article.

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