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Page 1
Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody.
Rosenfeld R, Noy-Porat T, Mechaly A, Makdasi E, Levy Y, Alcalay R, Falach R, Aftalion M, Epstein E, Gur D, Chitlaru T, Vitner EB, Melamed S, Politi B, Zauberman A, Lazar S, Beth-Din A, Evgy Y, Yitzhaki S, Shapira SC, Israely T, Mazor O. Rosenfeld R, et al. Among authors: gur d. Nat Commun. 2021 Feb 11;12(1):944. doi: 10.1038/s41467-021-21239-8. Nat Commun. 2021. PMID: 33574228 Free PMC article.
Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice.
Noy-Porat T, Mechaly A, Levy Y, Makdasi E, Alcalay R, Gur D, Aftalion M, Falach R, Leviatan Ben-Arye S, Lazar S, Zauberman A, Epstein E, Chitlaru T, Weiss S, Achdout H, Edgeworth JD, Kikkeri R, Yu H, Chen X, Yitzhaki S, Shapira SC, Padler-Karavani V, Mazor O, Rosenfeld R. Noy-Porat T, et al. Among authors: gur d. iScience. 2021 May 21;24(5):102479. doi: 10.1016/j.isci.2021.102479. Epub 2021 Apr 26. iScience. 2021. PMID: 33937725 Free PMC article.
Mice with induced pulmonary morbidities display severe lung inflammation and mortality following exposure to SARS-CoV-2.
Falach R, Bar-On L, Lazar S, Kadar T, Mazor O, Aftalion M, Gur D, Evgy Y, Shifman O, Aminov T, Israeli O, Cohen-Gihon I, Zaide G, Gutman H, Vagima Y, Makdasi E, Stein D, Rosenfeld R, Alcalay R, Zahavy E, Levy H, Glinert I, Ben-Shmuel A, Israely T, Melamed S, Politi B, Achdout H, Yitzhaki S, Kronman C, Sabo T. Falach R, et al. Among authors: gur d. JCI Insight. 2021 Jun 22;6(12):e145916. doi: 10.1172/jci.insight.145916. JCI Insight. 2021. PMID: 33974566 Free PMC article.
Lipid Nanoparticle RBD-hFc mRNA Vaccine Protects hACE2 Transgenic Mice against a Lethal SARS-CoV-2 Infection.
Elia U, Rotem S, Bar-Haim E, Ramishetti S, Naidu GS, Gur D, Aftalion M, Israeli M, Bercovich-Kinori A, Alcalay R, Makdasi E, Chitlaru T, Rosenfeld R, Israely T, Melamed S, Abutbul Ionita I, Danino D, Peer D, Cohen O. Elia U, et al. Among authors: gur d. Nano Lett. 2021 Jun 9;21(11):4774-4779. doi: 10.1021/acs.nanolett.1c01284. Epub 2021 May 25. Nano Lett. 2021. PMID: 34032435
The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against viral variants.
Makdasi E, Zvi A, Alcalay R, Noy-Porat T, Peretz E, Mechaly A, Levy Y, Epstein E, Chitlaru T, Tennenhouse A, Aftalion M, Gur D, Paran N, Tamir H, Zimhony O, Weiss S, Mandelboim M, Mendelson E, Zuckerman N, Nemet I, Kliker L, Yitzhaki S, Shapira SC, Israely T, Fleishman SJ, Mazor O, Rosenfeld R. Makdasi E, et al. Among authors: gur d. Cell Rep. 2021 Sep 7;36(10):109679. doi: 10.1016/j.celrep.2021.109679. Epub 2021 Aug 21. Cell Rep. 2021. PMID: 34464610 Free PMC article.
Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity.
Achdout H, Vitner EB, Politi B, Melamed S, Yahalom-Ronen Y, Tamir H, Erez N, Avraham R, Weiss S, Cherry L, Bar-Haim E, Makdasi E, Gur D, Aftalion M, Chitlaru T, Vagima Y, Paran N, Israely T. Achdout H, et al. Among authors: gur d. Nat Commun. 2021 Oct 5;12(1):5819. doi: 10.1038/s41467-021-26113-1. Nat Commun. 2021. PMID: 34611155 Free PMC article.
Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal Antibodies.
Noy-Porat T, Edri A, Alcalay R, Makdasi E, Gur D, Aftalion M, Evgy Y, Beth-Din A, Levy Y, Epstein E, Radinsky O, Zauberman A, Lazar S, Yitzhaki S, Marcus H, Porgador A, Rosenfeld R, Mazor O. Noy-Porat T, et al. Among authors: gur d. Antibodies (Basel). 2021 Nov 8;10(4):45. doi: 10.3390/antib10040045. Antibodies (Basel). 2021. PMID: 34842604 Free PMC article.
Prolonged Protective Immunity Induced by Mild SARS-CoV-2 Infection of K18-hACE2 Mice.
Bar-On L, Aftalion M, Makdasi E, Gur D, Alcalay R, Cohen H, Beth-Din A, Rosenfeld R, Achdout H, Bar-Haim E, Falach R, Chitlaru T, Cohen O. Bar-On L, et al. Among authors: gur d. Vaccines (Basel). 2022 Apr 14;10(4):613. doi: 10.3390/vaccines10040613. Vaccines (Basel). 2022. PMID: 35455362 Free PMC article.
514 results