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Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody.
Rosenfeld R, Noy-Porat T, Mechaly A, Makdasi E, Levy Y, Alcalay R, Falach R, Aftalion M, Epstein E, Gur D, Chitlaru T, Vitner EB, Melamed S, Politi B, Zauberman A, Lazar S, Beth-Din A, Evgy Y, Yitzhaki S, Shapira SC, Israely T, Mazor O. Rosenfeld R, et al. Among authors: shapira sc. Nat Commun. 2021 Feb 11;12(1):944. doi: 10.1038/s41467-021-21239-8. Nat Commun. 2021. PMID: 33574228 Free PMC article.
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes.
Noy-Porat T, Makdasi E, Alcalay R, Mechaly A, Levy Y, Bercovich-Kinori A, Zauberman A, Tamir H, Yahalom-Ronen Y, Israeli M, Epstein E, Achdout H, Melamed S, Chitlaru T, Weiss S, Peretz E, Rosen O, Paran N, Yitzhaki S, Shapira SC, Israely T, Mazor O, Rosenfeld R. Noy-Porat T, et al. Among authors: shapira sc. Nat Commun. 2020 Aug 27;11(1):4303. doi: 10.1038/s41467-020-18159-4. Nat Commun. 2020. PMID: 32855401 Free PMC article.
A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge.
Yahalom-Ronen Y, Tamir H, Melamed S, Politi B, Shifman O, Achdout H, Vitner EB, Israeli O, Milrot E, Stein D, Cohen-Gihon I, Lazar S, Gutman H, Glinert I, Cherry L, Vagima Y, Lazar S, Weiss S, Ben-Shmuel A, Avraham R, Puni R, Lupu E, Bar-David E, Sittner A, Erez N, Zichel R, Mamroud E, Mazor O, Levy H, Laskar O, Yitzhaki S, Shapira SC, Zvi A, Beth-Din A, Paran N, Israely T. Yahalom-Ronen Y, et al. Among authors: shapira sc. Nat Commun. 2020 Dec 16;11(1):6402. doi: 10.1038/s41467-020-20228-7. Nat Commun. 2020. PMID: 33328475 Free PMC article.
Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice.
Noy-Porat T, Mechaly A, Levy Y, Makdasi E, Alcalay R, Gur D, Aftalion M, Falach R, Leviatan Ben-Arye S, Lazar S, Zauberman A, Epstein E, Chitlaru T, Weiss S, Achdout H, Edgeworth JD, Kikkeri R, Yu H, Chen X, Yitzhaki S, Shapira SC, Padler-Karavani V, Mazor O, Rosenfeld R. Noy-Porat T, et al. Among authors: shapira sc. iScience. 2021 May 21;24(5):102479. doi: 10.1016/j.isci.2021.102479. Epub 2021 Apr 26. iScience. 2021. PMID: 33937725 Free PMC article.
The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against viral variants.
Makdasi E, Zvi A, Alcalay R, Noy-Porat T, Peretz E, Mechaly A, Levy Y, Epstein E, Chitlaru T, Tennenhouse A, Aftalion M, Gur D, Paran N, Tamir H, Zimhony O, Weiss S, Mandelboim M, Mendelson E, Zuckerman N, Nemet I, Kliker L, Yitzhaki S, Shapira SC, Israely T, Fleishman SJ, Mazor O, Rosenfeld R. Makdasi E, et al. Among authors: shapira sc. Cell Rep. 2021 Sep 7;36(10):109679. doi: 10.1016/j.celrep.2021.109679. Epub 2021 Aug 21. Cell Rep. 2021. PMID: 34464610 Free PMC article.
Monitoring Group Activity of Hamsters and Mice as a Novel Tool to Evaluate COVID-19 Progression, Convalescence, and rVSV-ΔG-Spike Vaccination Efficacy.
Melamed S, Politi B, Grauer E, Achdout H, Aftalion M, Gur D, Tamir H, Yahalom-Ronen Y, Maimon S, Yitzhak E, Weiss S, Rosner A, Erez N, Yitzhaki S, Shapira SC, Paran N, Mamroud E, Vagima Y, Israely T. Melamed S, et al. Among authors: shapira sc. Front Bioeng Biotechnol. 2021 Oct 1;9:737627. doi: 10.3389/fbioe.2021.737627. eCollection 2021. Front Bioeng Biotechnol. 2021. PMID: 34660558 Free PMC article.
Coding-Complete Genome Sequences of Two SARS-CoV-2 Isolates from Early Manifestations of COVID-19 in Israel.
Cohen-Gihon I, Israeli O, Shifman O, Stein D, Achdout H, Weiss S, Mandelboim M, Erster O, Regev-Yochay G, Segal G, Yitzhaki S, Shapira SC, Beth-Din A, Zvi A. Cohen-Gihon I, et al. Among authors: shapira sc. Microbiol Resour Announc. 2020 Jul 9;9(28):e00677-20. doi: 10.1128/MRA.00677-20. Microbiol Resour Announc. 2020. PMID: 32646911 Free PMC article.
Diagnosis of Imported Monkeypox, Israel, 2018.
Erez N, Achdout H, Milrot E, Schwartz Y, Wiener-Well Y, Paran N, Politi B, Tamir H, Israely T, Weiss S, Beth-Din A, Shifman O, Israeli O, Yitzhaki S, Shapira SC, Melamed S, Schwartz E. Erez N, et al. Among authors: shapira sc. Emerg Infect Dis. 2019 May;25(5):980-983. doi: 10.3201/eid2505.190076. Epub 2019 May 17. Emerg Infect Dis. 2019. PMID: 30848724 Free PMC article.
93 results