Makepeace CM - Search Results

1

Targeting primary and metastatic uveal melanoma with a G protein inhibitor.

Onken MD, Makepeace CM, Kaltenbronn KM, Choi J, Hernandez-Aya L, Weilbaecher KN, Piggott KD, Rao PK, Yuede CM, Dixon AJ, Osei-Owusu P, Cooper JA, Blumer KJ. Onken MD, et al. Among authors: makepeace cm. J Biol Chem. 2021 Jan-Jun;296:100403. doi: 10.1016/j.jbc.2021.100403. Epub 2021 Feb 10. J Biol Chem. 2021. PMID: 33577798 Free PMC article.

2

Transmembrane segment 3 of the Glut1 glucose transporter is an outer helix.

Mueckler M, Roach W, Makepeace C. Mueckler M, et al. J Biol Chem. 2004 Nov 5;279(45):46876-81. doi: 10.1074/jbc.M408632200. Epub 2004 Aug 10. J Biol Chem. 2004. PMID: 15308632 Free article.

3

Transmembrane segment 12 of the Glut1 glucose transporter is an outer helix and is not directly involved in the transport mechanism.

Mueckler M, Makepeace C. Mueckler M, et al. J Biol Chem. 2006 Dec 1;281(48):36993-8. doi: 10.1074/jbc.M608158200. Epub 2006 Oct 3. J Biol Chem. 2006. PMID: 17020877 Free article.

4

Transmembrane segment 6 of the Glut1 glucose transporter is an outer helix and contains amino acid side chains essential for transport activity.

Mueckler M, Makepeace C. Mueckler M, et al. J Biol Chem. 2008 Apr 25;283(17):11550-5. doi: 10.1074/jbc.M708896200. Epub 2008 Feb 1. J Biol Chem. 2008. PMID: 18245775 Free PMC article.

5

Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells.

Onken MD, Makepeace CM, Kaltenbronn KM, Kanai SM, Todd TD, Wang S, Broekelmann TJ, Rao PK, Cooper JA, Blumer KJ. Onken MD, et al. Among authors: makepeace cm. Sci Signal. 2018 Sep 4;11(546):eaao6852. doi: 10.1126/scisignal.aao6852. Sci Signal. 2018. PMID: 30181242 Free PMC article.

6

Oncogenic Gq/11 signaling acutely drives and chronically sustains metabolic reprogramming in uveal melanoma.

Onken MD, Noda SE, Kaltenbronn KM, Frankfater C, Makepeace CM, Fettig N, Piggott KD, Custer PL, Ippolito JE, Blumer KJ. Onken MD, et al. Among authors: makepeace cm. J Biol Chem. 2022 Jan;298(1):101495. doi: 10.1016/j.jbc.2021.101495. Epub 2021 Dec 14. J Biol Chem. 2022. PMID: 34919964 Free PMC article.

7

Protein Kinase Signaling Networks Driven by Oncogenic Gq/11 in Uveal Melanoma Identified by Phosphoproteomic and Bioinformatic Analyses.

Onken MD, Erdmann-Gilmore P, Zhang Q, Thapa K, King E, Kaltenbronn KM, Noda SE, Makepeace CM, Goldfarb D, Babur Ö, Townsend RR, Blumer KJ. Onken MD, et al. Among authors: makepeace cm. Mol Cell Proteomics. 2023 Nov;22(11):100649. doi: 10.1016/j.mcpro.2023.100649. Epub 2023 Sep 19. Mol Cell Proteomics. 2023. PMID: 37730182 Free PMC article.

8

Identification of an amino acid residue that lies between the exofacial vestibule and exofacial substrate-binding site of the Glut1 sugar permeation pathway.

Mueckler M, Makepeace C. Mueckler M, et al. J Biol Chem. 1997 Nov 28;272(48):30141-6. doi: 10.1074/jbc.272.48.30141. J Biol Chem. 1997. PMID: 9374494 Free article.

9

Transmembrane segment 5 of the Glut1 glucose transporter is an amphipathic helix that forms part of the sugar permeation pathway.

Mueckler M, Makepeace C. Mueckler M, et al. J Biol Chem. 1999 Apr 16;274(16):10923-6. doi: 10.1074/jbc.274.16.10923. J Biol Chem. 1999. PMID: 10196171 Free article.

10

Analysis of transmembrane segment 10 of the Glut1 glucose transporter by cysteine-scanning mutagenesis and substituted cysteine accessibility.

Mueckler M, Makepeace C. Mueckler M, et al. J Biol Chem. 2002 Feb 1;277(5):3498-503. doi: 10.1074/jbc.M109157200. Epub 2001 Nov 16. J Biol Chem. 2002. PMID: 11713254 Free article.

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