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A vitamin B12 conjugate of exendin-4 improves glucose tolerance without associated nausea or hypophagia in rodents.
Mietlicki-Baase EG, Liberini CG, Workinger JL, Bonaccorso RL, Borner T, Reiner DJ, Koch-Laskowski K, McGrath LE, Lhamo R, Stein LM, De Jonghe BC, Holz GG, Roth CL, Doyle RP, Hayes MR. Mietlicki-Baase EG, et al. Among authors: stein lm. Diabetes Obes Metab. 2018 May;20(5):1223-1234. doi: 10.1111/dom.13222. Epub 2018 Feb 20. Diabetes Obes Metab. 2018. PMID: 29327400 Free PMC article.
Hypothalamus-hippocampus circuitry regulates impulsivity via melanin-concentrating hormone.
Noble EE, Wang Z, Liu CM, Davis EA, Suarez AN, Stein LM, Tsan L, Terrill SJ, Hsu TM, Jung AH, Raycraft LM, Hahn JD, Darvas M, Cortella AM, Schier LA, Johnson AW, Hayes MR, Holschneider DP, Kanoski SE. Noble EE, et al. Among authors: stein lm. Nat Commun. 2019 Oct 29;10(1):4923. doi: 10.1038/s41467-019-12895-y. Nat Commun. 2019. PMID: 31664021 Free PMC article.
A second-generation glucagon-like peptide-1 receptor agonist mitigates vomiting and anorexia while retaining glucoregulatory potency in lean diabetic and emetic mammalian models.
Borner T, Shaulson ED, Tinsley IC, Stein LM, Horn CC, Hayes MR, Doyle RP, De Jonghe BC. Borner T, et al. Among authors: stein lm. Diabetes Obes Metab. 2020 Oct;22(10):1729-1741. doi: 10.1111/dom.14089. Epub 2020 Jun 25. Diabetes Obes Metab. 2020. PMID: 32410372 Free PMC article.
55 results