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Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening.
Gutbier S, Wanke F, Dahm N, Rümmelin A, Zimmermann S, Christensen K, Köchl F, Rautanen A, Hatje K, Geering B, Zhang JD, Britschgi M, Cowley SA, Patsch C. Gutbier S, et al. Among authors: cowley sa. Int J Mol Sci. 2020 Jul 7;21(13):4808. doi: 10.3390/ijms21134808. Int J Mol Sci. 2020. PMID: 32645954 Free PMC article.
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Hall-Roberts H, Agarwal D, Obst J, Smith TB, Monzón-Sandoval J, Di Daniel E, Webber C, James WS, Mead E, Davis JB, Cowley SA. Hall-Roberts H, et al. Among authors: cowley sa. Alzheimers Res Ther. 2020 Nov 16;12(1):151. doi: 10.1186/s13195-020-00709-z. Alzheimers Res Ther. 2020. PMID: 33198789 Free PMC article.
Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism.
Okarmus J, Havelund JF, Ryding M, Schmidt SI, Bogetofte H, Heon-Roberts R, Wade-Martins R, Cowley SA, Ryan BJ, Færgeman NJ, Hyttel P, Meyer M. Okarmus J, et al. Among authors: cowley sa. Stem Cell Reports. 2021 Jun 8;16(6):1510-1526. doi: 10.1016/j.stemcr.2021.04.022. Epub 2021 May 27. Stem Cell Reports. 2021. PMID: 34048689 Free PMC article.
Variation on a theme: mapping microglial heterogeneity.
Washer SJ, Bassett AR, Cowley SA. Washer SJ, et al. Among authors: cowley sa. Trends Genet. 2021 Dec;37(12):1050-1052. doi: 10.1016/j.tig.2021.09.004. Epub 2021 Sep 22. Trends Genet. 2021. PMID: 34563398
97 results