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Inhibitors of specific ceramide synthases.
Schiffmann S, Hartmann D, Fuchs S, Birod K, Ferreiròs N, Schreiber Y, Zivkovic A, Geisslinger G, Grösch S, Stark H. Schiffmann S, et al. Among authors: zivkovic a. Biochimie. 2012 Feb;94(2):558-65. doi: 10.1016/j.biochi.2011.09.007. Epub 2011 Sep 17. Biochimie. 2012. PMID: 21945810
Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice.
Imeri F, Fallegger D, Zivkovic A, Schwalm S, Enzmann G, Blankenbach K, Meyer zu Heringdorf D, Homann T, Kleuser B, Pfeilschifter J, Engelhardt B, Stark H, Huwiler A. Imeri F, et al. Among authors: zivkovic a. Neuropharmacology. 2014 Oct;85:314-27. doi: 10.1016/j.neuropharm.2014.05.012. Epub 2014 May 23. Neuropharmacology. 2014. PMID: 24863045
FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P(3) and phosphoinositide 3-kinase.
Imeri F, Blanchard O, Jenni A, Schwalm S, Wünsche C, Zivkovic A, Stark H, Pfeilschifter J, Huwiler A. Imeri F, et al. Among authors: zivkovic a. Naunyn Schmiedebergs Arch Pharmacol. 2015 Dec;388(12):1283-92. doi: 10.1007/s00210-015-1159-5. Epub 2015 Aug 13. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 26267293 Free article.
Ceramide synthesis regulates T cell activity and GVHD development.
Sofi MH, Heinrichs J, Dany M, Nguyen H, Dai M, Bastian D, Schutt S, Wu Y, Daenthanasanmak A, Gencer S, Zivkovic A, Szulc Z, Stark H, Liu C, Chang YJ, Ogretmen B, Yu XZ. Sofi MH, et al. Among authors: zivkovic a. JCI Insight. 2017 May 18;2(10):e91701. doi: 10.1172/jci.insight.91701. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515365 Free PMC article.
190 results