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PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways.
Vettel C, Lämmle S, Ewens S, Cervirgen C, Emons J, Ongherth A, Dewenter M, Lindner D, Westermann D, Nikolaev VO, Lutz S, Zimmermann WH, El-Armouche A. Vettel C, et al. Among authors: lutz s. Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1246-52. doi: 10.1152/ajpheart.00852.2013. Epub 2014 Feb 14. Am J Physiol Heart Circ Physiol. 2014. PMID: 24531807 Free article.
p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts.
Ongherth A, Pasch S, Wuertz CM, Nowak K, Kittana N, Weis CA, Jatho A, Vettel C, Tiburcy M, Toischer K, Hasenfuss G, Zimmermann WH, Wieland T, Lutz S. Ongherth A, et al. Among authors: lutz s. J Mol Cell Cardiol. 2015 Nov;88:39-54. doi: 10.1016/j.yjmcc.2015.09.009. Epub 2015 Sep 21. J Mol Cell Cardiol. 2015. PMID: 26392029
1,822 results