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Page 1
Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction.
Riveros-Mckay F, Weale ME, Moore R, Selzam S, Krapohl E, Sivley RM, Tarran WA, Sørensen P, Lachapelle AS, Griffiths JA, Saffari A, Deanfield J, Spencer CCA, Hippisley-Cox J, Hunter DJ, O'Sullivan JW, Ashley EA, Plagnol V, Donnelly P. Riveros-Mckay F, et al. Among authors: saffari a. Circ Genom Precis Med. 2021 Apr;14(2):e003304. doi: 10.1161/CIRCGEN.120.003304. Epub 2021 Mar 2. Circ Genom Precis Med. 2021. PMID: 33651632 Free PMC article.
Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries.
Weale ME, Riveros-Mckay F, Selzam S, Seth P, Moore R, Tarran WA, Gradovich E, Giner-Delgado C, Palmer D, Wells D, Saffari A, Sivley RM, Lachapelle AS, Wand H, Clarke SL, Knowles JW, O'Sullivan JW, Ashley EA, McVean G, Plagnol V, Donnelly P. Weale ME, et al. Among authors: saffari a. Am J Cardiol. 2021 Jun 1;148:157-164. doi: 10.1016/j.amjcard.2021.02.032. Epub 2021 Mar 3. Am J Cardiol. 2021. PMID: 33675770 Free article.
DNA methylation signatures associated with cardiometabolic risk factors in children from India and The Gambia: results from the EMPHASIS study.
Antoun E, Issarapu P, di Gravio C, Shrestha S, Betts M, Saffari A, Sahariah SA, Sankareswaran A, Arumalla M, Prentice AM, Fall CHD, Silver MJ, Chandak GR, Lillycrop KA; EMPHASIS study group. Antoun E, et al. Among authors: saffari a. Clin Epigenetics. 2022 Jan 9;14(1):6. doi: 10.1186/s13148-021-01213-3. Clin Epigenetics. 2022. PMID: 35000590 Free PMC article.
Candidate genes linking maternal nutrient exposure to offspring health via DNA methylation: a review of existing evidence in humans with specific focus on one-carbon metabolism.
James P, Sajjadi S, Tomar AS, Saffari A, Fall CHD, Prentice AM, Shrestha S, Issarapu P, Yadav DK, Kaur L, Lillycrop K, Silver M, Chandak GR; EMPHASIS study group. James P, et al. Among authors: saffari a. Int J Epidemiol. 2018 Dec 1;47(6):1910-1937. doi: 10.1093/ije/dyy153. Int J Epidemiol. 2018. PMID: 30137462 Free PMC article. Review.
Protocol for the EMPHASIS study; epigenetic mechanisms linking maternal pre-conceptional nutrition and children's health in India and Sub-Saharan Africa.
Chandak GR, Silver MJ, Saffari A, Lillycrop KA, Shrestha S, Sahariah SA, Di Gravio C, Goldberg G, Tomar AS, Betts M, Sajjadi S, Acolatse L, James P, Issarapu P, Kumaran K, Potdar RD, Prentice AM, Fall CH. Chandak GR, et al. Among authors: saffari a. BMC Nutr. 2017 Oct 30;3:81. doi: 10.1186/s40795-017-0200-0. BMC Nutr. 2017. PMID: 30820326 Free PMC article.
Effect of maternal preconceptional and pregnancy micronutrient interventions on children's DNA methylation: Findings from the EMPHASIS study.
Saffari A, Shrestha S, Issarapu P, Sajjadi S, Betts M, Sahariah SA, Tomar AS, James P, Dedaniya A, Yadav DK, Kumaran K, Prentice AM, Lillycrop KA, Fall CHD, Chandak GR, Silver MJ; EMPHASIS Study Group. Saffari A, et al. Am J Clin Nutr. 2020 Oct 1;112(4):1099-1113. doi: 10.1093/ajcn/nqaa193. Am J Clin Nutr. 2020. PMID: 32889533 Free PMC article.
Environmentally sensitive hotspots in the methylome of the early human embryo.
Silver MJ, Saffari A, Kessler NJ, Chandak GR, Fall CHD, Issarapu P, Dedaniya A, Betts M, Moore SE, Routledge MN, Herceg Z, Cuenin C, Derakhshan M, James PT, Monk D, Prentice AM. Silver MJ, et al. Among authors: saffari a. Elife. 2022 Feb 21;11:e72031. doi: 10.7554/eLife.72031. Elife. 2022. PMID: 35188105 Free PMC article.
Epigenetic supersimilarity of monozygotic twin pairs.
Van Baak TE, Coarfa C, Dugué PA, Fiorito G, Laritsky E, Baker MS, Kessler NJ, Dong J, Duryea JD, Silver MJ, Saffari A, Prentice AM, Moore SE, Ghantous A, Routledge MN, Gong YY, Herceg Z, Vineis P, Severi G, Hopper JL, Southey MC, Giles GG, Milne RL, Waterland RA. Van Baak TE, et al. Among authors: saffari a. Genome Biol. 2018 Jan 9;19(1):2. doi: 10.1186/s13059-017-1374-0. Genome Biol. 2018. PMID: 29310692 Free PMC article.
Bigmelon: tools for analysing large DNA methylation datasets.
Gorrie-Stone TJ, Smart MC, Saffari A, Malki K, Hannon E, Burrage J, Mill J, Kumari M, Schalkwyk LC. Gorrie-Stone TJ, et al. Among authors: saffari a. Bioinformatics. 2019 Mar 15;35(6):981-986. doi: 10.1093/bioinformatics/bty713. Bioinformatics. 2019. PMID: 30875430 Free PMC article.
110 results