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Page 1
Discovery of a dual pathway aggregation mechanism for a therapeutic constrained peptide.
Chen T, Tang S, Hecht ES, Yen CW, Andersen N, Chin S, Cadang L, Roper B, Estevez A, Rohou A, Chang D, Dai L, Liu P, Al-Sayah M, Nagapudi K, Lin F, Famili A, Hu C, Kuhn R, Stella C, Crittenden CM, Gruenhagen JA, Venkatramani C, Hannoush RN, Leung D, Vandlen R, Yehl P. Chen T, et al. Among authors: cadang l. J Pharm Sci. 2021 Jun;110(6):2362-2371. doi: 10.1016/j.xphs.2020.12.041. Epub 2021 Feb 27. J Pharm Sci. 2021. PMID: 33652014
Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation.
Wei B, Gao X, Cadang L, Izadi S, Liu P, Zhang HM, Hecht E, Shim J, Magill G, Pabon JR, Dai L, Phung W, Lin E, Wang C, Whang K, Sanchez S, Oropeza J Jr, Camperi J, Zhang J, Sandoval W, Zhang YT, Jiang G. Wei B, et al. Among authors: cadang l. MAbs. 2021 Jan-Dec;13(1):1893427. doi: 10.1080/19420862.2021.1893427. MAbs. 2021. PMID: 33682619 Free PMC article.
Function-structure approach reveals novel insights on the interplay of Immunoglobulin G 1 proteoforms and Fc gamma receptor IIa allotypes.
Lippold S, Mistry K, Lenka S, Whang K, Liu P, Pitschi S, Kuhne F, Reusch D, Cadang L, Knaupp A, Izadi S, Dunkle A, Yang F, Schlothauer T. Lippold S, et al. Among authors: cadang l. Front Immunol. 2023 Sep 18;14:1260446. doi: 10.3389/fimmu.2023.1260446. eCollection 2023. Front Immunol. 2023. PMID: 37790943 Free PMC article.
CD3 Target Affinity Chromatography Mass Spectrometry as a New Tool for Function-Structure Characterization of T-Cell Engaging Bispecific Antibody Proteoforms and Product-Related Variants.
Lippold S, Hook M, Spick C, Knaupp A, Whang K, Ruperti F, Cadang L, Andersen N, Vogt A, Grote M, Reusch D, Haberger M, Yang F, Schlothauer T. Lippold S, et al. Among authors: cadang l. Anal Chem. 2023 Jan 31;95(4):2260-2268. doi: 10.1021/acs.analchem.2c03827. Epub 2023 Jan 13. Anal Chem. 2023. PMID: 36638115