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Page 1
7-Fluorosialyl Glycosides Are Hydrolysis Resistant but Readily Assembled by Sialyltransferases Providing Easy Access to More Metabolically Stable Glycoproteins.
Geissner A, Baumann L, Morley TJ, Wong AKO, Sim L, Rich JR, So PPL, Dullaghan EM, Lessard E, Iqbal U, Moreno M, Wakarchuk WW, Withers SG. Geissner A, et al. Among authors: dullaghan em. ACS Cent Sci. 2021 Feb 24;7(2):345-354. doi: 10.1021/acscentsci.0c01589. Epub 2021 Jan 19. ACS Cent Sci. 2021. PMID: 33655072 Free PMC article.
Development of Novel Monoamine Oxidase-B (MAO-B) Inhibitors with Reduced Blood-Brain Barrier Permeability for the Potential Management of Noncentral Nervous System (CNS) Diseases.
Gealageas R, Devineau A, So PPL, Kim CMJ, Surendradoss J, Buchwalder C, Heller M, Goebeler V, Dullaghan EM, Grierson DS, Putnins EE. Gealageas R, et al. Among authors: dullaghan em. J Med Chem. 2018 Aug 23;61(16):7043-7064. doi: 10.1021/acs.jmedchem.7b01588. Epub 2018 Aug 1. J Med Chem. 2018. PMID: 30016860
Discovery and optimization of a new class of pyruvate kinase inhibitors as potential therapeutics for the treatment of methicillin-resistant Staphylococcus aureus infections.
Kumar NS, Dullaghan EM, Finlay BB, Gong H, Reiner NE, Jon Paul Selvam J, Thorson LM, Campbell S, Vitko N, Richardson AR, Zoraghi R, Young RN. Kumar NS, et al. Among authors: dullaghan em. Bioorg Med Chem. 2014 Mar 1;22(5):1708-25. doi: 10.1016/j.bmc.2014.01.020. Epub 2014 Jan 24. Bioorg Med Chem. 2014. PMID: 24508307 Free PMC article.
Hormonal modulators of glial ABCA1 and apoE levels.
Fan J, Shimizu Y, Chan J, Wilkinson A, Ito A, Tontonoz P, Dullaghan E, Galea LA, Pfeifer T, Wellington CL. Fan J, et al. J Lipid Res. 2013 Nov;54(11):3139-50. doi: 10.1194/jlr.M042473. Epub 2013 Sep 2. J Lipid Res. 2013. PMID: 23999864 Free PMC article.
An anti-infective peptide that selectively modulates the innate immune response.
Scott MG, Dullaghan E, Mookherjee N, Glavas N, Waldbrook M, Thompson A, Wang A, Lee K, Doria S, Hamill P, Yu JJ, Li Y, Donini O, Guarna MM, Finlay BB, North JR, Hancock RE. Scott MG, et al. Nat Biotechnol. 2007 Apr;25(4):465-72. doi: 10.1038/nbt1288. Epub 2007 Mar 25. Nat Biotechnol. 2007. PMID: 17384586
15 results