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Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects.
Kiss T, Giles CB, Tarantini S, Yabluchanskiy A, Balasubramanian P, Gautam T, Csipo T, Nyúl-Tóth Á, Lipecz A, Szabo C, Farkas E, Wren JD, Csiszar A, Ungvari Z. Kiss T, et al. Geroscience. 2019 Aug;41(4):419-439. doi: 10.1007/s11357-019-00095-x. Epub 2019 Aug 28. Geroscience. 2019. PMID: 31463647 Free PMC article.
Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
Wiedenhoeft T, Tarantini S, Nyúl-Tóth Á, Yabluchanskiy A, Csipo T, Balasubramanian P, Lipecz A, Kiss T, Csiszar A, Csiszar A, Ungvari Z. Wiedenhoeft T, et al. Geroscience. 2019 Dec;41(6):711-725. doi: 10.1007/s11357-019-00102-1. Epub 2019 Oct 25. Geroscience. 2019. PMID: 31654270 Free PMC article.
Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases.
Ungvari Z, Tarantini S, Nyúl-Tóth Á, Kiss T, Yabluchanskiy A, Csipo T, Balasubramanian P, Lipecz A, Benyo Z, Csiszar A. Ungvari Z, et al. Geroscience. 2019 Dec;41(6):727-738. doi: 10.1007/s11357-019-00107-w. Epub 2019 Oct 26. Geroscience. 2019. PMID: 31655958 Free PMC article. Review.
Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans.
Csipo T, Mukli P, Lipecz A, Tarantini S, Bahadli D, Abdulhussein O, Owens C, Kiss T, Balasubramanian P, Nyúl-Tóth Á, Hand RA, Yabluchanska V, Sorond FA, Csiszar A, Ungvari Z, Yabluchanskiy A. Csipo T, et al. Geroscience. 2019 Oct;41(5):495-509. doi: 10.1007/s11357-019-00122-x. Epub 2019 Nov 2. Geroscience. 2019. PMID: 31676966 Free PMC article. Review.
Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging.
Tarantini S, Yabluchanskiy A, Csipo T, Fulop G, Kiss T, Balasubramanian P, DelFavero J, Ahire C, Ungvari A, Nyúl-Tóth Á, Farkas E, Benyo Z, Tóth A, Csiszar A, Ungvari Z. Tarantini S, et al. Geroscience. 2019 Oct;41(5):533-542. doi: 10.1007/s11357-019-00101-2. Epub 2019 Nov 2. Geroscience. 2019. PMID: 31679124 Free PMC article.
Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice.
Yabluchanskiy A, Tarantini S, Balasubramanian P, Kiss T, Csipo T, Fülöp GA, Lipecz A, Ahire C, DelFavero J, Nyul-Toth A, Sonntag WE, Schwartzman ML, Campisi J, Csiszar A, Ungvari Z. Yabluchanskiy A, et al. Geroscience. 2020 Apr;42(2):409-428. doi: 10.1007/s11357-020-00154-8. Epub 2020 Jan 20. Geroscience. 2020. PMID: 31960269 Free PMC article.
Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
Kiss T, Nyúl-Tóth Á, Balasubramanian P, Tarantini S, Ahire C, Yabluchanskiy A, Csipo T, Farkas E, Wren JD, Garman L, Csiszar A, Ungvari Z. Kiss T, et al. Geroscience. 2020 Apr;42(2):527-546. doi: 10.1007/s11357-020-00165-5. Epub 2020 Feb 13. Geroscience. 2020. PMID: 32056076 Free PMC article.
Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood.
Kiss T, Tarantini S, Csipo T, Balasubramanian P, Nyúl-Tóth Á, Yabluchanskiy A, Wren JD, Garman L, Huffman DM, Csiszar A, Ungvari Z. Kiss T, et al. Geroscience. 2020 Apr;42(2):727-748. doi: 10.1007/s11357-020-00180-6. Epub 2020 Mar 15. Geroscience. 2020. PMID: 32172434 Free PMC article.
63 results