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Page 1
AMPK-regulated miRNA-210-3p is activated during ischaemic neuronal injury and modulates PI3K-p70S6K signalling.
Pfeiffer S, Tomašcová A, Mamrak U, Haunsberger SJ, Connolly NMC, Resler A, Düssmann H, Weisová P, Jirström E, D'Orsi B, Chen G, Cremona M, Hennessy BT, Plesnila N, Prehn JHM. Pfeiffer S, et al. Among authors: jirstrom e. J Neurochem. 2021 Nov;159(4):710-728. doi: 10.1111/jnc.15347. Epub 2021 Mar 18. J Neurochem. 2021. PMID: 33694332 Free article.
Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration.
Baindoor S, Gibriel HAY, Venø MT, Su J, Morrissey EP, Jirström E, Woods I, Kenny A, Alves M, Halang L, Fabbrizio P, Bilen M, Engel T, Hogg MC, Bendotti C, Nardo G, Slack RS, Kjems J, Prehn JHM. Baindoor S, et al. Among authors: jirstrom e. Dis Model Mech. 2024 Nov 1;17(11):dmm050870. doi: 10.1242/dmm.050870. Epub 2024 Nov 18. Dis Model Mech. 2024. PMID: 39552337 Free PMC article.
tRNA-derived fragments are altered in diabetes.
Ng N, Gibriel HAY, Halang L, Jirström E, Ioana JA, Burke M, Byrne MM, Prehn JHM. Ng N, et al. Among authors: jirstrom e. Diabet Med. 2024 Feb;41(2):e15258. doi: 10.1111/dme.15258. Epub 2023 Nov 20. Diabet Med. 2024. PMID: 37935454
Quantification of substoichiometric modification reveals global tsRNA hypomodification, preferences for angiogenin-mediated tRNA cleavage, and idiosyncratic epitranscriptomes of human neuronal cell-lines.
Pichot F, Hogg MC, Marchand V, Bourguignon V, Jirström E, Farrell C, Gibriel HA, Prehn JHM, Motorin Y, Helm M. Pichot F, et al. Among authors: jirstrom e. Comput Struct Biotechnol J. 2022 Dec 19;21:401-417. doi: 10.1016/j.csbj.2022.12.020. eCollection 2023. Comput Struct Biotechnol J. 2022. PMID: 36618980 Free PMC article.