Sun W - Search Results

1

Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome.

Zhang X, Zhu B, Sun W, Wang M, Albarazanji K, Ghosh B, Cummings M, Lenhard J, Leonard J, Macielag M, Lanter J. Zhang X, et al. Among authors: sun w. Bioorg Med Chem Lett. 2021 May 15;40:127939. doi: 10.1016/j.bmcl.2021.127939. Epub 2021 Mar 11. Bioorg Med Chem Lett. 2021. PMID: 33713780

2

Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits.

Sun W, Zhang X, Cummings MD, Albarazanji K, Wu J, Wang M, Alexander R, Zhu B, Zhang Y, Leonard J, Lanter J, Lenhard J. Sun W, et al. J Pharmacol Exp Ther. 2020 Dec;375(3):510-521. doi: 10.1124/jpet.120.000219. Epub 2020 Oct 8. J Pharmacol Exp Ther. 2020. PMID: 33033171

3

Optimization of a pyrazole hit from FBDD into a novel series of indazoles as ketohexokinase inhibitors.

Zhang X, Song F, Kuo GH, Xiang A, Gibbs AC, Abad MC, Sun W, Kuo LC, Sui Z. Zhang X, et al. Among authors: sun w. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4762-7. doi: 10.1016/j.bmcl.2011.06.067. Epub 2011 Jun 29. Bioorg Med Chem Lett. 2011. PMID: 21767952

4

Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease.

Lu T, Connolly PJ, Philippar U, Sun W, Cummings MD, Barbay K, Gys L, Van Nuffel L, Austin N, Bekkers M, Shen F, Cai A, Attar R, Meerpoel L, Edwards J. Lu T, et al. Among authors: sun w. Bioorg Med Chem Lett. 2019 Dec 1;29(23):126743. doi: 10.1016/j.bmcl.2019.126743. Epub 2019 Oct 17. Bioorg Med Chem Lett. 2019. PMID: 31678006

5

Electron density guided fragment-based lead discovery of ketohexokinase inhibitors.

Gibbs AC, Abad MC, Zhang X, Tounge BA, Lewandowski FA, Struble GT, Sun W, Sui Z, Kuo LC. Gibbs AC, et al. Among authors: sun w. J Med Chem. 2010 Nov 25;53(22):7979-91. doi: 10.1021/jm100677s. Epub 2010 Oct 29. J Med Chem. 2010. PMID: 21033679

6

A Chemical Probe for the Methyl Transferase PRMT5 with a Novel Binding Mode.

Pande V, Sun W, Beke L, Berthelot D, Brehmer D, Brown D, Corbera J, Irving S, Meerpoel L, Nys T, Parade M, Robinson C, Sommen C, Viellevoye M, Wu T, Thuring JW. Pande V, et al. Among authors: sun w. ACS Med Chem Lett. 2020 Sep 28;11(11):2227-2231. doi: 10.1021/acsmedchemlett.0c00355. eCollection 2020 Nov 12. ACS Med Chem Lett. 2020. PMID: 33214833 Free PMC article.

7

Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity.

Brehmer D, Beke L, Wu T, Millar HJ, Moy C, Sun W, Mannens G, Pande V, Boeckx A, van Heerde E, Nys T, Gustin EM, Verbist B, Zhou L, Fan Y, Bhargava V, Safabakhsh P, Vinken P, Verhulst T, Gilbert A, Rai S, Graubert TA, Pastore F, Fiore D, Gu J, Johnson A, Philippar U, Morschhäuser B, Walker D, De Lange D, Keersmaekers V, Viellevoye M, Diels G, Schepens W, Thuring JW, Meerpoel L, Packman K, Lorenzi MV, Laquerre S. Brehmer D, et al. Among authors: sun w. Mol Cancer Ther. 2021 Dec;20(12):2317-2328. doi: 10.1158/1535-7163.MCT-21-0367. Epub 2021 Sep 28. Mol Cancer Ther. 2021. PMID: 34583982 Free PMC article.

8

Preparation of 4'-Spirocyclobutyl Nucleoside Analogues as Novel and Versatile Adenosine Scaffolds.

Verhoeven J, De Vleeschouwer F, Kong H, Van Hecke K, Pande V, Sun W, Vos A, Wu T, Meerpoel L, Thuring JW, Verniest G. Verhoeven J, et al. Among authors: sun w. Chemistry. 2019 Dec 2;25(67):15419-15423. doi: 10.1002/chem.201904574. Epub 2019 Nov 4. Chemistry. 2019. PMID: 31609050

9

Synthesis and Reactivity of Spirocarbocycles as Scaffolds for Nucleoside Analogues.

Verhoeven J, Deraet X, Pande V, Sun W, Alonso M, De Proft F, Meerpoel L, Thuring JW, Verniest G. Verhoeven J, et al. Among authors: sun w. J Org Chem. 2020 Dec 4;85(23):14989-15005. doi: 10.1021/acs.joc.0c01825. Epub 2020 Nov 16. J Org Chem. 2020. PMID: 33196210

10

Genetic diversity analysis and core collection construction of tea plant from the Yunnan Province of China using ddRAD sequencing.

Sun W, Chen C, Xu L, Tao L, Tong X, Tian Y, Jiang H, Chen L, Wen H, Liu S, Wei C, Zhu J. Sun W, et al. BMC Plant Biol. 2024 Dec 4;24(1):1163. doi: 10.1186/s12870-024-05821-y. BMC Plant Biol. 2024. PMID: 39627747

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

20,493 results

Search Page

Filters