Chen YC - Search Results

1

A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity.

Khaled HG, Feng H, Hu X, Sun X, Zheng W, Li PP, Rudnicki DD, Ye W, Chen YC, Southall N, Marugan J, Ross CA, Ferrer M, Henderson MJ, Margolis RL. Khaled HG, et al. Among authors: chen yc. Sci Rep. 2021 Mar 17;11(1):6157. doi: 10.1038/s41598-021-85279-2. Sci Rep. 2021. PMID: 33731741 Free PMC article.

2

Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.

Al-Ramahi I, Giridharan SSP, Chen YC, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, Ferrer M, Southall N, Weisman LS, Botas J, Marugan JJ. Al-Ramahi I, et al. Among authors: chen yc. Elife. 2017 Dec 26;6:e29123. doi: 10.7554/eLife.29123. Elife. 2017. PMID: 29256861 Free PMC article.

3

A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.

Asawa RR, Danchik C, Zakharov A, Chen Y, Voss T, Jadhav A, Wallace DP, Trott JF, Weiss RH, Simeonov A, Martinez NJ. Asawa RR, et al. Sci Rep. 2020 Mar 6;10(1):4203. doi: 10.1038/s41598-020-61082-3. Sci Rep. 2020. PMID: 32144367 Free PMC article.

4

Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer.

Esquer H, Zhou Q, Nemkov T, Abraham AD, Rinaldetti S, Chen YC, Zhang X, Orman MV, D'Alessandro A, Ferrer M, Messersmith WA, LaBarbera DV. Esquer H, et al. Among authors: chen yc. Oncogene. 2021 Apr;40(16):2884-2897. doi: 10.1038/s41388-021-01728-2. Epub 2021 Mar 19. Oncogene. 2021. PMID: 33742123 Free PMC article.

5

Pharmacological activation of STING blocks SARS-CoV-2 infection.

Li M, Ferretti M, Ying B, Descamps H, Lee E, Dittmar M, Lee JS, Whig K, Kamalia B, Dohnalová L, Uhr G, Zarkoob H, Chen YC, Ramage H, Ferrer M, Lynch K, Schultz DC, Thaiss CA, Diamond MS, Cherry S. Li M, et al. Among authors: chen yc. Sci Immunol. 2021 May 18;6(59):eabi9007. doi: 10.1126/sciimmunol.abi9007. Sci Immunol. 2021. PMID: 34010142 Free PMC article.

6

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model.

Dorjsuren D, Eastman RT, Song MJ, Yasgar A, Chen Y, Bharti K, Zakharov AV, Jadhav A, Ferrer M, Shi PY, Simeonov A. Dorjsuren D, et al. PLoS One. 2022 Jan 18;17(1):e0261821. doi: 10.1371/journal.pone.0261821. eCollection 2022. PLoS One. 2022. PMID: 35041689 Free PMC article.

7

A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids.

Boutin ME, Strong CE, Van Hese B, Hu X, Itkin Z, Chen YC, LaCroix A, Gordon R, Guicherit O, Carromeu C, Kundu S, Lee E, Ferrer M. Boutin ME, et al. Among authors: chen yc. SLAS Discov. 2022 Jun;27(4):209-218. doi: 10.1016/j.slasd.2022.01.003. Epub 2022 Jan 31. SLAS Discov. 2022. PMID: 35092840 Free PMC article.

8

Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform.

Jung O, Tung YT, Sim E, Chen YC, Lee E, Ferrer M, Song MJ. Jung O, et al. Among authors: chen yc. Biofabrication. 2022 Feb 14;14(2):10.1088/1758-5090/ac32a5. doi: 10.1088/1758-5090/ac32a5. Biofabrication. 2022. PMID: 35166694 Free PMC article.

9

Author Correction: A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.

Asawa RR, Danchik C, Zakharov A, Chen Y, Voss T, Jadhav A, Wallace DP, Trott JF, Weiss RH, Simeonov A, Martinez NJ. Asawa RR, et al. Sci Rep. 2022 Oct 13;12(1):17185. doi: 10.1038/s41598-022-21947-1. Sci Rep. 2022. PMID: 36229506 Free PMC article. No abstract available.

10

Functional brain region-specific neural spheroids for modeling neurological diseases and therapeutics screening.

Strong CE, Zhang J, Carrasco M, Kundu S, Boutin M, Vishwasrao HD, Liu J, Medina A, Chen YC, Wilson K, Lee EM, Ferrer M. Strong CE, et al. Among authors: chen yc. Commun Biol. 2023 Nov 28;6(1):1211. doi: 10.1038/s42003-023-05582-8. Commun Biol. 2023. PMID: 38017066 Free PMC article.

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