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Page 1
A blueprint for pursuing therapeutic interventions and early phase clinical trials in clonal haematopoiesis.
Haque T, Shastri A, Desai P, Xie Z, Hammond D, King Z, Kishtagari A, Madanat YF, Abaza Y, Silver AJ, Singh A, Borate UM, Heimlich JB, Slosky DA, Bolton KL, Patnaik MS, Bick AG, Verma AK, Jaiswal S, Steensma DP, Savona MR. Haque T, et al. Among authors: silver aj. Br J Haematol. 2024 Dec 9. doi: 10.1111/bjh.19925. Online ahead of print. Br J Haematol. 2024. PMID: 39653653 Review.
Germline genetics, disease, and exposure to medication influence longitudinal dynamics of clonal hematopoiesis.
Mack T, Pershad Y, Vlasschaert C, Bejan CA, Heimlich JB, Li Y, Mickels NA, Van Amburg JC, Ulloa J, Silver AJ, Luo LY, Jones A, Ferrell PB, Kishtagari A, Xu Y, Savona MR, Bick AG. Mack T, et al. Among authors: silver aj. Haematologica. 2024 Nov 14. doi: 10.3324/haematol.2024.286513. Online ahead of print. Haematologica. 2024. PMID: 39540221 Free article.
Loss-of-function mutations in Dnmt3a and Tet2 lead to accelerated atherosclerosis and concordant macrophage phenotypes.
Rauch PJ, Gopakumar J, Silver AJ, Nachun D, Ahmad H, McConkey M, Nakao T, Bosse M, Rentz T, Vivanco Gonzalez N, Greenwald NF, McCaffrey EF, Khair Z, Gopakumar M, Rodrigues KB, Lin AE, Sinha E, Fefer M, Cohen DN, Vromman A, Shvartz E, Sukhova G, Bendall S, Angelo M, Libby P, Ebert BL, Jaiswal S. Rauch PJ, et al. Among authors: silver aj. Nat Cardiovasc Res. 2023 Sep;2(9):805-818. doi: 10.1038/s44161-023-00326-7. Epub 2023 Sep 4. Nat Cardiovasc Res. 2023. PMID: 39196062
Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies.
Meyer CT, Smith BN, Wang J, Teuscher KB, Grieb BC, Howard GC, Silver AJ, Lorey SL, Stott GM, Moore WJ, Lee T, Savona MR, Weissmiller AM, Liu Q, Quaranta V, Fesik SW, Tansey WP. Meyer CT, et al. Among authors: silver aj. Proc Natl Acad Sci U S A. 2024 Aug 27;121(35):e2408889121. doi: 10.1073/pnas.2408889121. Epub 2024 Aug 21. Proc Natl Acad Sci U S A. 2024. PMID: 39167600
Investigating iRHOM2-Associated Transcriptional Changes in Tylosis With Esophageal Cancer.
Murtough S, Babu D, Webb CM, Louis Dit Picard H, McGinty LA, Chao-Chu J, Pink R, Silver AR, Smart HL, Field JK, Woodland P, Risk JM, Blaydon DC, Pennington DJ, Kelsell DP. Murtough S, et al. Among authors: silver ar. Gastro Hep Adv. 2023 Dec 26;3(3):385-395. doi: 10.1016/j.gastha.2023.12.007. eCollection 2024. Gastro Hep Adv. 2023. PMID: 39131151 Free PMC article.
701 results