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De novo assembly and delivery to mouse cells of a 101 kb functional human gene.
Mitchell LA, McCulloch LH, Pinglay S, Berger H, Bosco N, Brosh R, Bulajić M, Huang E, Hogan MS, Martin JA, Mazzoni EO, Davoli T, Maurano MT, Boeke JD. Mitchell LA, et al. Among authors: bosco n. Genetics. 2021 May 17;218(1):iyab038. doi: 10.1093/genetics/iyab038. Genetics. 2021. PMID: 33742653 Free PMC article.
KaryoCreate: A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres.
Bosco N, Goldberg A, Zhao X, Mays JC, Cheng P, Johnson AF, Bianchi JJ, Toscani C, Di Tommaso E, Katsnelson L, Annuar D, Mei S, Faitelson RE, Pesselev IY, Mohamed KS, Mermerian A, Camacho-Hernandez EM, Gionco CA, Manikas J, Tseng YS, Sun Z, Fani S, Keegan S, Lippman SM, Fenyö D, Giunta S, Santaguida S, Davoli T. Bosco N, et al. Cell. 2023 Apr 27;186(9):1985-2001.e19. doi: 10.1016/j.cell.2023.03.029. Epub 2023 Apr 18. Cell. 2023. PMID: 37075754 Free PMC article.
Structural variant evolution after telomere crisis.
Dewhurst SM, Yao X, Rosiene J, Tian H, Behr J, Bosco N, Takai KK, de Lange T, Imieliński M. Dewhurst SM, et al. Among authors: bosco n. Nat Commun. 2021 Apr 7;12(1):2093. doi: 10.1038/s41467-021-21933-7. Nat Commun. 2021. PMID: 33828097 Free PMC article.
Chromothripsis and Kataegis Induced by Telomere Crisis.
Maciejowski J, Li Y, Bosco N, Campbell PJ, de Lange T. Maciejowski J, et al. Among authors: bosco n. Cell. 2015 Dec 17;163(7):1641-54. doi: 10.1016/j.cell.2015.11.054. Cell. 2015. PMID: 26687355 Free PMC article.
79 results