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Comparing the efficacy of γ- and electron-irradiation of PBMCs to promote secretion of paracrine, regenerative factors.
Laggner M, Gugerell A, Copic D, Jeitler M, Springer M, Peterbauer A, Kremslehner C, Filzwieser-Narzt M, Gruber F, Madlener S, Erb M, Widder J, Lechner W, Georg D, Mildner M, Ankersmit HJ. Laggner M, et al. Mol Ther Methods Clin Dev. 2021 Feb 24;21:14-27. doi: 10.1016/j.omtm.2021.02.016. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 33768126 Free PMC article.
A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids.
Narzt MS, Nagelreiter IM, Oskolkova O, Bochkov VN, Latreille J, Fedorova M, Ni Z, Sialana FJ, Lubec G, Filzwieser M, Laggner M, Bilban M, Mildner M, Tschachler E, Grillari J, Gruber F. Narzt MS, et al. Among authors: laggner m. Redox Biol. 2019 Jan;20:467-482. doi: 10.1016/j.redox.2018.11.006. Epub 2018 Nov 13. Redox Biol. 2019. PMID: 30466060 Free PMC article.
Different pro-angiogenic potential of γ-irradiated PBMC-derived secretome and its subfractions.
Wagner T, Traxler D, Simader E, Beer L, Narzt MS, Gruber F, Madlener S, Laggner M, Erb M, Vorstandlechner V, Gugerell A, Radtke C, Gnecchi M, Peterbauer A, Gschwandtner M, Tschachler E, Keibl C, Slezak P, Ankersmit HJ, Mildner M. Wagner T, et al. Among authors: laggner m. Sci Rep. 2018 Dec 20;8(1):18016. doi: 10.1038/s41598-018-36928-6. Sci Rep. 2018. PMID: 30573762 Free PMC article.
Toxicological testing of allogeneic secretome derived from peripheral mononuclear cells (APOSEC): a novel cell-free therapeutic agent in skin disease.
Wuschko S, Gugerell A, Chabicovsky M, Hofbauer H, Laggner M, Erb M, Ostler T, Peterbauer A, Suessner S, Demyanets S, Leuschner J, Moser B, Mildner M, Ankersmit HJ. Wuschko S, et al. Among authors: laggner m. Sci Rep. 2019 Apr 3;9(1):5598. doi: 10.1038/s41598-019-42057-5. Sci Rep. 2019. PMID: 30944367 Free PMC article.
Tissue-regenerative potential of the secretome of γ-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis.
Simader E, Beer L, Laggner M, Vorstandlechner V, Gugerell A, Erb M, Kalinina P, Copic D, Moser D, Spittler A, Tschachler E, Jan Ankersmit H, Mildner M. Simader E, et al. Among authors: laggner m. Cell Death Dis. 2019 Sep 30;10(10):729. doi: 10.1038/s41419-019-1974-6. Cell Death Dis. 2019. PMID: 31570701 Free PMC article.
Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products.
Laggner M, Gugerell A, Bachmann C, Hofbauer H, Vorstandlechner V, Seibold M, Gouya Lechner G, Peterbauer A, Madlener S, Demyanets S, Sorgenfrey D, Ostler T, Erb M, Mildner M, Ankersmit HJ. Laggner M, et al. Stem Cell Res Ther. 2020 Jan 3;11(1):9. doi: 10.1186/s13287-019-1524-2. Stem Cell Res Ther. 2020. PMID: 31900195 Free PMC article.
43 results