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Promises and challenges of adoptive T-cell therapies for solid tumours.
Morotti M, Albukhari A, Alsaadi A, Artibani M, Brenton JD, Curbishley SM, Dong T, Dustin ML, Hu Z, McGranahan N, Miller ML, Santana-Gonzalez L, Seymour LW, Shi T, Van Loo P, Yau C, White H, Wietek N, Church DN, Wedge DC, Ahmed AA. Morotti M, et al. Br J Cancer. 2021 May;124(11):1759-1776. doi: 10.1038/s41416-021-01353-6. Epub 2021 Mar 29. Br J Cancer. 2021. PMID: 33782566 Free PMC article. Review.
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.
Choudhry H, Albukhari A, Morotti M, Haider S, Moralli D, Smythies J, Schödel J, Green CM, Camps C, Buffa F, Ratcliffe P, Ragoussis J, Harris AL, Mole DR. Choudhry H, et al. Among authors: morotti m. Oncogene. 2015 Aug 20;34(34):4482-90. doi: 10.1038/onc.2014.378. Epub 2014 Nov 24. Oncogene. 2015. PMID: 25417700 Free PMC article.
An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment.
Motohara T, Masuda K, Morotti M, Zheng Y, El-Sahhar S, Chong KY, Wietek N, Alsaadi A, Carrami EM, Hu Z, Artibani M, Gonzalez LS, Katabuchi H, Saya H, Ahmed AA. Motohara T, et al. Among authors: morotti m. Oncogene. 2019 Apr;38(16):2885-2898. doi: 10.1038/s41388-018-0637-x. Epub 2018 Dec 19. Oncogene. 2019. PMID: 30568223 Free PMC article. Review.
The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells.
Hu Z, Artibani M, Alsaadi A, Wietek N, Morotti M, Shi T, Zhong Z, Santana Gonzalez L, El-Sahhar S, Carrami EM, Mallett G, Feng Y, Masuda K, Zheng Y, Chong K, Damato S, Dhar S, Campo L, Garruto Campanile R, Soleymani Majd H, Rai V, Maldonado-Perez D, Jones S, Cerundolo V, Sauka-Spengler T, Yau C, Ahmed AA. Hu Z, et al. Among authors: morotti m. Cancer Cell. 2020 Feb 10;37(2):226-242.e7. doi: 10.1016/j.ccell.2020.01.003. Cancer Cell. 2020. PMID: 32049047 Free article.
A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals.
Demetriou P, Abu-Shah E, Valvo S, McCuaig S, Mayya V, Kvalvaag A, Starkey T, Korobchevskaya K, Lee LYW, Friedrich M, Mann E, Kutuzov MA, Morotti M, Wietek N, Rada H, Yusuf S, Afrose J, Siokis A; Oxford IBD Cohort Investigators; Meyer-Hermann M, Ahmed AA, Depoil D, Dustin ML. Demetriou P, et al. Among authors: morotti m. Nat Immunol. 2020 Oct;21(10):1232-1243. doi: 10.1038/s41590-020-0770-x. Epub 2020 Sep 14. Nat Immunol. 2020. PMID: 32929275 Free PMC article.
Author Correction: A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals.
Demetriou P, Abu-Shah E, Valvo S, McCuaig S, Mayya V, Kvalvaag A, Starkey T, Korobchevskaya K, Lee LYW, Friedrich M, Mann E, Kutuzov MA, Morotti M, Wietek N, Rada H, Yusuf S, Afrose J, Siokis A; Oxford IBD Cohort Investigators; Meyer-Hermann M, Ahmed AA, Depoil D, Dustin ML. Demetriou P, et al. Among authors: morotti m. Nat Immunol. 2021 Jan;22(1):99. doi: 10.1038/s41590-020-00825-w. Nat Immunol. 2021. PMID: 33122852 No abstract available.
Mechanistic Drivers of Müllerian Duct Development and Differentiation Into the Oviduct.
Santana Gonzalez L, Rota IA, Artibani M, Morotti M, Hu Z, Wietek N, Alsaadi A, Albukhari A, Sauka-Spengler T, Ahmed AA. Santana Gonzalez L, et al. Among authors: morotti m. Front Cell Dev Biol. 2021 Mar 8;9:605301. doi: 10.3389/fcell.2021.605301. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33763415 Free PMC article. Review.
Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor-initiating cells.
Artibani M, Masuda K, Hu Z, Rauher PC, Mallett G, Wietek N, Morotti M, Chong K, KaramiNejadRanjbar M, Zois CE, Dhar S, El-Sahhar S, Campo L, Blagden SP, Damato S, Pathiraja PN, Nicum S, Gleeson F, Laios A, Alsaadi A, Santana Gonzalez L, Motohara T, Albukhari A, Lu Z, Bast RC Jr, Harris AL, Ejsing CS, Klemm RW, Yau C, Sauka-Spengler T, Ahmed AA. Artibani M, et al. Among authors: morotti m. JCI Insight. 2021 Jun 8;6(11):e147929. doi: 10.1172/jci.insight.147929. JCI Insight. 2021. PMID: 33945502 Free PMC article.
Correction to: An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment.
Motohara T, Masuda K, Morotti M, Zheng Y, El-Sahhar S, Chong KY, Wietek N, Alsaadi A, Carrami EM, Hu Z, Artibani M, Gonzalez LS, Katabuchi H, Saya H, Ahmed AA. Motohara T, et al. Among authors: morotti m. Oncogene. 2022 Jul;41(27):3584. doi: 10.1038/s41388-022-02356-0. Oncogene. 2022. PMID: 35662285 Free PMC article. No abstract available.
Patient-reported outcomes in adoptive cell-therapy trials: mind the gap.
Ghisoni E, Morotti M, Colomer-Lahiguera S, Eicher M, Coukos G, Trueb L, Di Maio M. Ghisoni E, et al. Among authors: morotti m. J Immunother Cancer. 2022 Dec;10(12):e006082. doi: 10.1136/jitc-2022-006082. J Immunother Cancer. 2022. PMID: 36600604 Free PMC article.
86 results