Clemens TL - Search Results

1

Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts.

Zhang Q, Mesner LD, Calabrese GM, Dirckx N, Li Z, Verardo A, Yang Q, Tower RJ, Faugere MC, Farber CR, Clemens TL. Zhang Q, et al. Among authors: clemens tl. J Clin Invest. 2021 Apr 1;131(7):e142580. doi: 10.1172/JCI142580. J Clin Invest. 2021. PMID: 33792563 Free PMC article.

2

Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism.

Dirckx N, Tower RJ, Mercken EM, Vangoitsenhoven R, Moreau-Triby C, Breugelmans T, Nefyodova E, Cardoen R, Mathieu C, Van der Schueren B, Confavreux CB, Clemens TL, Maes C. Dirckx N, et al. Among authors: clemens tl. J Clin Invest. 2018 Mar 1;128(3):1087-1105. doi: 10.1172/JCI97794. Epub 2018 Feb 12. J Clin Invest. 2018. PMID: 29431735 Free PMC article.

3

The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage.

Zhang Q, Riddle RC, Yang Q, Rosen CR, Guttridge DC, Dirckx N, Faugere MC, Farber CR, Clemens TL. Zhang Q, et al. Among authors: clemens tl. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17980-17989. doi: 10.1073/pnas.1905489116. Epub 2019 Aug 21. Proc Natl Acad Sci U S A. 2019. PMID: 31434789 Free PMC article.

4

Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition.

Fulzele K, Riddle RC, DiGirolamo DJ, Cao X, Wan C, Chen D, Faugere MC, Aja S, Hussain MA, Brüning JC, Clemens TL. Fulzele K, et al. Among authors: clemens tl. Cell. 2010 Jul 23;142(2):309-19. doi: 10.1016/j.cell.2010.06.002. Cell. 2010. PMID: 20655471 Free PMC article.

5

Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.

Riddle RC, Diegel CR, Leslie JM, Van Koevering KK, Faugere MC, Clemens TL, Williams BO. Riddle RC, et al. Among authors: clemens tl. PLoS One. 2013 May 10;8(5):e63323. doi: 10.1371/journal.pone.0063323. Print 2013. PLoS One. 2013. PMID: 23675479 Free PMC article.

6

Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast.

Frey JL, Li Z, Ellis JM, Zhang Q, Farber CR, Aja S, Wolfgang MJ, Clemens TL, Riddle RC. Frey JL, et al. Among authors: clemens tl. Mol Cell Biol. 2015 Jun 1;35(11):1979-91. doi: 10.1128/MCB.01343-14. Epub 2015 Mar 23. Mol Cell Biol. 2015. PMID: 25802278 Free PMC article.

7

Dysregulated TGF-β signaling alters bone microstructure in a mouse model of Loeys-Dietz syndrome.

Dewan AK, Tomlinson RE, Mitchell S, Goh BC, Yung RM, Kumar S, Tan EW, Faugere MC, Dietz HC 3rd, Clemens TL, Sponseller PD. Dewan AK, et al. Among authors: clemens tl. J Orthop Res. 2015 Oct;33(10):1447-54. doi: 10.1002/jor.22920. Epub 2015 Jul 14. J Orthop Res. 2015. PMID: 26173585 Free article.

8

Glucose Transporter-4 Facilitates Insulin-Stimulated Glucose Uptake in Osteoblasts.

Li Z, Frey JL, Wong GW, Faugere MC, Wolfgang MJ, Kim JK, Riddle RC, Clemens TL. Li Z, et al. Among authors: clemens tl. Endocrinology. 2016 Nov;157(11):4094-4103. doi: 10.1210/en.2016-1583. Epub 2016 Sep 30. Endocrinology. 2016. PMID: 27689415 Free PMC article.

9

Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass.

Goh BC, Singhal V, Herrera AJ, Tomlinson RE, Kim S, Faugere MC, Germain-Lee EL, Clemens TL, Lee SJ, DiGirolamo DJ. Goh BC, et al. Among authors: clemens tl. J Biol Chem. 2017 Aug 18;292(33):13809-13822. doi: 10.1074/jbc.M117.782128. Epub 2017 Jun 28. J Biol Chem. 2017. PMID: 28659341 Free PMC article.

10

The role of osteoblasts in energy homeostasis.

Dirckx N, Moorer MC, Clemens TL, Riddle RC. Dirckx N, et al. Among authors: clemens tl. Nat Rev Endocrinol. 2019 Nov;15(11):651-665. doi: 10.1038/s41574-019-0246-y. Epub 2019 Aug 28. Nat Rev Endocrinol. 2019. PMID: 31462768 Free PMC article. Review.

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