Qiao J - Search Results

1

Antimicrobial peptide DP7 with potential activity against SARS coronavirus infections.

Zhang R, Jiang X, Qiao J, Wang Z, Tong A, Yang J, Yang S, Yang L. Zhang R, et al. Among authors: qiao j. Signal Transduct Target Ther. 2021 Apr 1;6(1):140. doi: 10.1038/s41392-021-00551-1. Signal Transduct Target Ther. 2021. PMID: 33795636 Free PMC article. No abstract available.

2

Discovery of 1,8-disubstituted-[1,2,3]triazolo[4,5-c]quinoline derivatives as a new class of Hippo signaling pathway inhibitors.

Qiao J, Lin G, Xia A, Xiang Z, Chen P, Zhang G, Li L, Yang S. Qiao J, et al. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2595-2603. doi: 10.1016/j.bmcl.2019.08.001. Epub 2019 Aug 2. Bioorg Med Chem Lett. 2019. PMID: 31400941

3

Crystal structure of SARS-CoV-2 nsp10/nsp16 2'-O-methylase and its implication on antiviral drug design.

Lin S, Chen H, Ye F, Chen Z, Yang F, Zheng Y, Cao Y, Qiao J, Yang S, Lu G. Lin S, et al. Among authors: qiao j. Signal Transduct Target Ther. 2020 Jul 29;5(1):131. doi: 10.1038/s41392-020-00241-4. Signal Transduct Target Ther. 2020. PMID: 32728018 Free PMC article. No abstract available.

4

Discovery of Potent Small-Molecule SIRT6 Activators: Structure-Activity Relationship and Anti-Pancreatic Ductal Adenocarcinoma Activity.

Chen X, Sun W, Huang S, Zhang H, Lin G, Li H, Qiao J, Li L, Yang S. Chen X, et al. Among authors: qiao j. J Med Chem. 2020 Sep 24;63(18):10474-10495. doi: 10.1021/acs.jmedchem.0c01183. Epub 2020 Sep 9. J Med Chem. 2020. PMID: 32787077

5

SARS-CoV-2 M^pro inhibitors with antiviral activity in a transgenic mouse model.

Qiao J, Li YS, Zeng R, Liu FL, Luo RH, Huang C, Wang YF, Zhang J, Quan B, Shen C, Mao X, Liu X, Sun W, Yang W, Ni X, Wang K, Xu L, Duan ZL, Zou QC, Zhang HL, Qu W, Long YH, Li MH, Yang RC, Liu X, You J, Zhou Y, Yao R, Li WP, Liu JM, Chen P, Liu Y, Lin GF, Yang X, Zou J, Li L, Hu Y, Lu GW, Li WM, Wei YQ, Zheng YT, Lei J, Yang S. Qiao J, et al. Science. 2021 Mar 26;371(6536):1374-1378. doi: 10.1126/science.abf1611. Epub 2021 Feb 18. Science. 2021. PMID: 33602867 Free PMC article.

6

An orally available M^pro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron.

Quan BX, Shuai H, Xia AJ, Hou Y, Zeng R, Liu XL, Lin GF, Qiao JX, Li WP, Wang FL, Wang K, Zhou RJ, Yuen TT, Chen MX, Yoon C, Wu M, Zhang SY, Huang C, Wang YF, Yang W, Tian C, Li WM, Wei YQ, Yuen KY, Chan JF, Lei J, Chu H, Yang S. Quan BX, et al. Among authors: qiao jx. Nat Microbiol. 2022 May;7(5):716-725. doi: 10.1038/s41564-022-01119-7. Epub 2022 Apr 27. Nat Microbiol. 2022. PMID: 35477751

7

A new generation M^pro inhibitor with potent activity against SARS-CoV-2 Omicron variants.

Huang C, Shuai H, Qiao J, Hou Y, Zeng R, Xia A, Xie L, Fang Z, Li Y, Yoon C, Huang Q, Hu B, You J, Quan B, Zhao X, Guo N, Zhang S, Ma R, Zhang J, Wang Y, Yang R, Zhang S, Nan J, Xu H, Wang F, Lei J, Chu H, Yang S. Huang C, et al. Among authors: qiao j. Signal Transduct Target Ther. 2023 Mar 16;8(1):128. doi: 10.1038/s41392-023-01392-w. Signal Transduct Target Ther. 2023. PMID: 36928316 Free PMC article.

8

Discovery of benzodiazepine derivatives as a new class of covalent inhibitors of SARS-CoV-2 main protease.

Wang F, Zeng R, Qiao J, Xia A, Li Y, Li F, Wu Y, Liu Y, Zhao X, Lei J, Yang S. Wang F, et al. Among authors: qiao j. Bioorg Med Chem Lett. 2023 Aug 15;92:129407. doi: 10.1016/j.bmcl.2023.129407. Epub 2023 Jul 10. Bioorg Med Chem Lett. 2023. PMID: 37437852

9

Discovery and structure-activity relationship studies of novel α-ketoamide derivatives targeting the SARS-CoV-2 main protease.

Huang C, Zeng R, Qiao J, Quan B, Luo R, Huang Q, Guo N, Li Y, Long X, Ma R, Xia A, Fang Z, Wang Y, Li Y, Zheng Y, Li L, Lei J, Yang S. Huang C, et al. Among authors: qiao j. Eur J Med Chem. 2023 Nov 5;259:115657. doi: 10.1016/j.ejmech.2023.115657. Epub 2023 Jul 20. Eur J Med Chem. 2023. PMID: 37517202

10

Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groups.

Huang Q, Quan B, Chen Y, Zhao X, Zhou Y, Huang C, Qiao J, Wang Y, Li Y, Yang S, Lei J, Li L. Huang Q, et al. Among authors: qiao j. Bioorg Chem. 2024 Feb;143:107001. doi: 10.1016/j.bioorg.2023.107001. Epub 2023 Dec 6. Bioorg Chem. 2024. PMID: 38101266

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