Scott AM - Search Results

1

EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism.

Gomez J, Areeb Z, Stuart SF, Nguyen HPT, Paradiso L, Zulkifli A, Madan S, Rajagopal V, Montgomery MK, Gan HK, Scott AM, Jones J, Kaye AH, Morokoff AP, Luwor RB. Gomez J, et al. Among authors: scott am. Cancers (Basel). 2021 Mar 10;13(6):1198. doi: 10.3390/cancers13061198. Cancers (Basel). 2021. PMID: 33801941 Free PMC article.

2

Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor.

Mishima K, Johns TG, Luwor RB, Scott AM, Stockert E, Jungbluth AA, Ji XD, Suvarna P, Voland JR, Old LJ, Huang HJ, Cavenee WK. Mishima K, et al. Among authors: scott am. Cancer Res. 2001 Jul 15;61(14):5349-54. Cancer Res. 2001. PMID: 11454673

3

Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR.

Luwor RB, Johns TG, Murone C, Huang HJ, Cavenee WK, Ritter G, Old LJ, Burgess AW, Scott AM. Luwor RB, et al. Among authors: scott am. Cancer Res. 2001 Jul 15;61(14):5355-61. Cancer Res. 2001. PMID: 11454674

4

Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478.

Johns TG, Luwor RB, Murone C, Walker F, Weinstock J, Vitali AA, Perera RM, Jungbluth AA, Stockert E, Old LJ, Nice EC, Burgess AW, Scott AM. Johns TG, et al. Among authors: scott am. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15871-6. doi: 10.1073/pnas.2036503100. Epub 2003 Dec 15. Proc Natl Acad Sci U S A. 2003. PMID: 14676326 Free PMC article.

5

The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR.

Luwor RB, Zhu HJ, Walker F, Vitali AA, Perera RM, Burgess AW, Scott AM, Johns TG. Luwor RB, et al. Among authors: scott am. Oncogene. 2004 Aug 12;23(36):6095-104. doi: 10.1038/sj.onc.1207870. Oncogene. 2004. PMID: 15221011

6

Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.

Perera RM, Narita Y, Furnari FB, Gan HK, Murone C, Ahlkvist M, Luwor RB, Burgess AW, Stockert E, Jungbluth AA, Old LJ, Cavenee WK, Scott AM, Johns TG. Perera RM, et al. Among authors: scott am. Clin Cancer Res. 2005 Sep 1;11(17):6390-9. doi: 10.1158/1078-0432.CCR-04-2653. Clin Cancer Res. 2005. PMID: 16144944

7

The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.

Gan HK, Walker F, Burgess AW, Rigopoulos A, Scott AM, Johns TG. Gan HK, et al. Among authors: scott am. J Biol Chem. 2007 Feb 2;282(5):2840-50. doi: 10.1074/jbc.M605136200. Epub 2006 Nov 8. J Biol Chem. 2007. PMID: 17092939 Free article.

8

Targeting a unique EGFR epitope with monoclonal antibody 806 activates NF-kappaB and initiates tumour vascular normalization.

Gan HK, Lappas M, Cao DX, Cvrljevdic A, Scott AM, Johns TG. Gan HK, et al. Among authors: scott am. J Cell Mol Med. 2009 Sep;13(9B):3993-4001. doi: 10.1111/j.1582-4934.2009.00783.x. Epub 2009 May 11. J Cell Mol Med. 2009. PMID: 19432811 Free PMC article.

9

Immuno-PET quantitation of de2-7 epidermal growth factor receptor expression in glioma using 124I-IMP-R4-labeled antibody ch806.

Lee FT, O'Keefe GJ, Gan HK, Mountain AJ, Jones GR, Saunder TH, Sagona J, Rigopoulos A, Smyth FE, Johns TG, Govindan SV, Goldenberg DM, Old LJ, Scott AM. Lee FT, et al. Among authors: scott am. J Nucl Med. 2010 Jun;51(6):967-72. doi: 10.2967/jnumed.109.068395. Epub 2010 May 19. J Nucl Med. 2010. PMID: 20484439 Free article.

10

MAb 806 enhances the efficacy of ionizing radiation in glioma xenografts expressing the de2-7 epidermal growth factor receptor.

Johns TG, McKay MJ, Cvrljevic AN, Gan HK, Taylor C, Xu H, Smyth FE, Scott AM. Johns TG, et al. Among authors: scott am. Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):572-8. doi: 10.1016/j.ijrobp.2010.03.027. Epub 2010 Jul 16. Int J Radiat Oncol Biol Phys. 2010. PMID: 20638193

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