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The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a β-thalassemia mouse model.
Matte A, Federti E, Kung C, Kosinski PA, Narayanaswamy R, Russo R, Federico G, Carlomagno F, Desbats MA, Salviati L, Leboeuf C, Valenti MT, Turrini F, Janin A, Yu S, Beneduce E, Ronseaux S, Iatcenko I, Dang L, Ganz T, Jung CL, Iolascon A, Brugnara C, De Franceschi L. Matte A, et al. Among authors: federico g. J Clin Invest. 2021 May 17;131(10):e144206. doi: 10.1172/JCI144206. J Clin Invest. 2021. PMID: 33822774 Free PMC article.
Identification of Novel Small Molecule Inhibitors of Oncogenic RET Kinase.
Moccia M, Liu Q, Guida T, Federico G, Brescia A, Zhao Z, Choi HG, Deng X, Tan L, Wang J, Billaud M, Gray NS, Carlomagno F, Santoro M. Moccia M, et al. Among authors: federico g. PLoS One. 2015 Jun 5;10(6):e0128364. doi: 10.1371/journal.pone.0128364. eCollection 2015. PLoS One. 2015. PMID: 26046350 Free PMC article.
NCOA4 Deficiency Impairs Systemic Iron Homeostasis.
Bellelli R, Federico G, Matte' A, Colecchia D, Iolascon A, Chiariello M, Santoro M, De Franceschi L, Carlomagno F. Bellelli R, et al. Among authors: federico g. Cell Rep. 2016 Jan 26;14(3):411-421. doi: 10.1016/j.celrep.2015.12.065. Epub 2016 Jan 14. Cell Rep. 2016. PMID: 26776506 Free article.
Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis.
Matte A, De Falco L, Federti E, Cozzi A, Iolascon A, Levi S, Mohandas N, Zamo A, Bruno M, Lebouef C, Janin A, Siciliano A, Ganz T, Federico G, Carlomagno F, Mueller S, Silva I, Carbone C, Melisi D, Kim DW, Choi SY, De Franceschi L. Matte A, et al. Among authors: federico g. Antioxid Redox Signal. 2018 Jan 1;28(1):1-14. doi: 10.1089/ars.2017.7051. Epub 2017 Sep 6. Antioxid Redox Signal. 2018. PMID: 28793778
NCOA4 links iron bioavailability to DNA metabolism.
Federico G, Carrillo F, Dapporto F, Chiariello M, Santoro M, Bellelli R, Carlomagno F. Federico G, et al. Cell Rep. 2022 Aug 16;40(7):111207. doi: 10.1016/j.celrep.2022.111207. Cell Rep. 2022. PMID: 35977492 Free article.
238 results