Cancelas JA - Search Results

1

Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics.

Serrano-Lopez J, Hegde S, Kumar S, Serrano J, Fang J, Wellendorf AM, Roche PA, Rangel Y, Carrington LJ, Geiger H, Grimes HL, Luther S, Maillard I, Sanchez-Garcia J, Starczynowski DT, Cancelas JA. Serrano-Lopez J, et al. Among authors: cancelas ja. Elife. 2021 Apr 8;10:e66190. doi: 10.7554/eLife.66190. Elife. 2021. PMID: 33830019 Free PMC article.

2

Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow.

Yang L, Wang L, Geiger H, Cancelas JA, Mo J, Zheng Y. Yang L, et al. Among authors: cancelas ja. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5091-6. doi: 10.1073/pnas.0610819104. Epub 2007 Mar 12. Proc Natl Acad Sci U S A. 2007. PMID: 17360364 Free PMC article.

3

Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential.

Williams JP, Wu J, Johansson G, Rizvi TA, Miller SC, Geiger H, Malik P, Li W, Mukouyama YS, Cancelas JA, Ratner N. Williams JP, et al. Among authors: cancelas ja. Cell Stem Cell. 2008 Dec 4;3(6):658-69. doi: 10.1016/j.stem.2008.10.003. Cell Stem Cell. 2008. PMID: 19041782 Free PMC article.

4

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen.

Kalfa TA, Pushkaran S, Zhang X, Johnson JF, Pan D, Daria D, Geiger H, Cancelas JA, Williams DA, Zheng Y. Kalfa TA, et al. Among authors: cancelas ja. Haematologica. 2010 Jan;95(1):27-35. doi: 10.3324/haematol.2009.006239. Haematologica. 2010. PMID: 20065081 Free PMC article.

5

Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization.

Ryan MA, Nattamai KJ, Xing E, Schleimer D, Daria D, Sengupta A, Köhler A, Liu W, Gunzer M, Jansen M, Ratner N, Le Cras TD, Waterstrat A, Van Zant G, Cancelas JA, Zheng Y, Geiger H. Ryan MA, et al. Among authors: cancelas ja. Nat Med. 2010 Oct;16(10):1141-6. doi: 10.1038/nm.2217. Epub 2010 Sep 26. Nat Med. 2010. PMID: 20871610 Free PMC article.

6

R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization.

Shang X, Cancelas JA, Li L, Guo F, Liu W, Johnson JF, Ficker A, Daria D, Geiger H, Ratner N, Zheng Y. Shang X, et al. Among authors: cancelas ja. J Biol Chem. 2011 Jul 8;286(27):24068-78. doi: 10.1074/jbc.M111.226951. Epub 2011 May 13. J Biol Chem. 2011. PMID: 21572048 Free PMC article.

7

Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation.

Sengupta A, Duran A, Ishikawa E, Florian MC, Dunn SK, Ficker AM, Leitges M, Geiger H, Diaz-Meco M, Moscat J, Cancelas JA. Sengupta A, et al. Among authors: cancelas ja. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9957-62. doi: 10.1073/pnas.1103132108. Epub 2011 Jun 8. Proc Natl Acad Sci U S A. 2011. PMID: 21653884 Free PMC article.

8

Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity.

Geiger H, Pawar SA, Kerschen EJ, Nattamai KJ, Hernandez I, Liang HP, Fernández JÁ, Cancelas JA, Ryan MA, Kustikova O, Schambach A, Fu Q, Wang J, Fink LM, Petersen KU, Zhou D, Griffin JH, Baum C, Weiler H, Hauer-Jensen M. Geiger H, et al. Among authors: cancelas ja. Nat Med. 2012 Jul;18(7):1123-9. doi: 10.1038/nm.2813. Nat Med. 2012. PMID: 22729286 Free PMC article.

9

Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated β1/β2-integrin trafficking.

Taniguchi Ishikawa E, Chang KH, Nayak R, Olsson HA, Ficker AM, Dunn SK, Madhu MN, Sengupta A, Whitsett JA, Grimes HL, Cancelas JA. Taniguchi Ishikawa E, et al. Among authors: cancelas ja. Nat Commun. 2013;4:1660. doi: 10.1038/ncomms2645. Nat Commun. 2013. PMID: 23552075 Free PMC article.

10

p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment.

Raman R, Kumar RS, Hinge A, Kumar S, Nayak R, Xu J, Szczur K, Cancelas JA, Filippi MD. Raman R, et al. Among authors: cancelas ja. Leukemia. 2013 Nov;27(11):2209-19. doi: 10.1038/leu.2013.103. Epub 2013 Apr 8. Leukemia. 2013. PMID: 23563238 Free PMC article.

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