Wang C - Search Results

1

Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.

Wang C, Xiong M, Gratuze M, Bao X, Shi Y, Andhey PS, Manis M, Schroeder C, Yin Z, Madore C, Butovsky O, Artyomov M, Ulrich JD, Holtzman DM. Wang C, et al. Neuron. 2021 May 19;109(10):1657-1674.e7. doi: 10.1016/j.neuron.2021.03.024. Epub 2021 Apr 7. Neuron. 2021. PMID: 33831349 Free PMC article.

2

Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model.

Huynh TV, Wang C, Tran AC, Tabor GT, Mahan TE, Francis CM, Finn MB, Spellman R, Manis M, Tanzi RE, Ulrich JD, Holtzman DM. Huynh TV, et al. Among authors: wang c. Mol Neurodegener. 2019 Oct 17;14(1):37. doi: 10.1186/s13024-019-0337-1. Mol Neurodegener. 2019. PMID: 31623648 Free PMC article.

3

APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.

Xiong M, Jiang H, Serrano JR, Gonzales ER, Wang C, Gratuze M, Hoyle R, Bien-Ly N, Silverman AP, Sullivan PM, Watts RJ, Ulrich JD, Zipfel GJ, Holtzman DM. Xiong M, et al. Among authors: wang c. Sci Transl Med. 2021 Feb 17;13(581):eabd7522. doi: 10.1126/scitranslmed.abd7522. Sci Transl Med. 2021. PMID: 33597265 Free PMC article.

4

Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol.

Wang H, Kulas JA, Wang C, Holtzman DM, Ferris HA, Hansen SB. Wang H, et al. Among authors: wang c. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2102191118. doi: 10.1073/pnas.2102191118. Proc Natl Acad Sci U S A. 2021. PMID: 34385305 Free PMC article.

5

Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains.

Bigley TM, Xiong M, Ali M, Chen Y, Wang C, Serrano JR, Eteleeb A, Harari O, Yang L, Patel SJ, Cruchaga C, Yokoyama WM, Holtzman DM. Bigley TM, et al. Among authors: wang c. Mol Neurodegener. 2022 Jan 15;17(1):10. doi: 10.1186/s13024-021-00514-8. Mol Neurodegener. 2022. PMID: 35033173 Free PMC article.

6

Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.

Mahan TE, Wang C, Bao X, Choudhury A, Ulrich JD, Holtzman DM. Mahan TE, et al. Among authors: wang c. Mol Neurodegener. 2022 Feb 2;17(1):13. doi: 10.1186/s13024-022-00516-0. Mol Neurodegener. 2022. PMID: 35109920 Free PMC article.

7

Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy.

Xiong M, Wang C, Gratuze M, Saadi F, Bao X, Bosch ME, Lee C, Jiang H, Serrano JR, Gonzales ER, Kipnis M, Holtzman DM. Xiong M, et al. Among authors: wang c. Mol Neurodegener. 2023 Mar 16;18(1):17. doi: 10.1186/s13024-023-00610-x. Mol Neurodegener. 2023. PMID: 36922879 Free PMC article.

8

Tauopathy severely disrupts homeostatic set-points in emergent neural dynamics but not in the activity of individual neurons.

McGregor JN, Farris CA, Ensley S, Schneider A, Wang C, Liu Y, Tu J, Elmore H, Ronayne KD, Wessel R, Dyer EL, Bhaskaran-Nair K, Holtzman DM, Hengen KB. McGregor JN, et al. Among authors: wang c. bioRxiv [Preprint]. 2023 Sep 6:2023.09.01.555947. doi: 10.1101/2023.09.01.555947. bioRxiv. 2023. PMID: 37732214 Free PMC article. Preprint.

9

Failure in a population: Tauopathy disrupts homeostatic set-points in emergent dynamics despite stability in the constituent neurons.

McGregor JN, Farris CA, Ensley S, Schneider A, Fosque LJ, Wang C, Tilden EI, Liu Y, Tu J, Elmore H, Ronayne KD, Wessel R, Dyer EL, Bhaskaran-Nair K, Holtzman DM, Hengen KB. McGregor JN, et al. Among authors: wang c. Neuron. 2024 Nov 6;112(21):3567-3584.e5. doi: 10.1016/j.neuron.2024.08.006. Epub 2024 Sep 5. Neuron. 2024. PMID: 39241778 Free article.

10

Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice.

Li Y, Chen H, Wang J, Wang J, Niu X, Wang C, Qin D, Li F, Wang Y, Xiong J, Liu S, Huang L, Zhang X, Gao F, Gao D, Fan M, Xiao X, Wang ZH. Li Y, et al. Among authors: wang zh, wang j, wang y, wang c. Front Mol Neurosci. 2022 Dec 12;15:1068164. doi: 10.3389/fnmol.2022.1068164. eCollection 2022. Front Mol Neurosci. 2022. PMID: 36578534 Free PMC article.

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