Hekselman I - Search Results

1

The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones.

Shemesh N, Jubran J, Dror S, Simonovsky E, Basha O, Argov C, Hekselman I, Abu-Qarn M, Vinogradov E, Mauer O, Tiago T, Carra S, Ben-Zvi A, Yeger-Lotem E. Shemesh N, et al. Among authors: hekselman i. Nat Commun. 2021 Apr 12;12(1):2180. doi: 10.1038/s41467-021-22369-9. Nat Commun. 2021. PMID: 33846299 Free PMC article.

2

The TissueNet v.2 database: A quantitative view of protein-protein interactions across human tissues.

Basha O, Barshir R, Sharon M, Lerman E, Kirson BF, Hekselman I, Yeger-Lotem E. Basha O, et al. Among authors: hekselman i. Nucleic Acids Res. 2017 Jan 4;45(D1):D427-D431. doi: 10.1093/nar/gkw1088. Epub 2016 Nov 29. Nucleic Acids Res. 2017. PMID: 27899616 Free PMC article.

3

Role of duplicate genes in determining the tissue-selectivity of hereditary diseases.

Barshir R, Hekselman I, Shemesh N, Sharon M, Novack L, Yeger-Lotem E. Barshir R, et al. Among authors: hekselman i. PLoS Genet. 2018 May 3;14(5):e1007327. doi: 10.1371/journal.pgen.1007327. eCollection 2018 May. PLoS Genet. 2018. PMID: 29723191 Free PMC article.

4

Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes.

Elyahu Y, Hekselman I, Eizenberg-Magar I, Berner O, Strominger I, Schiller M, Mittal K, Nemirovsky A, Eremenko E, Vital A, Simonovsky E, Chalifa-Caspi V, Friedman N, Yeger-Lotem E, Monsonego A. Elyahu Y, et al. Among authors: hekselman i. Sci Adv. 2019 Aug 21;5(8):eaaw8330. doi: 10.1126/sciadv.aaw8330. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31457092 Free PMC article.

5

Mechanisms of tissue and cell-type specificity in heritable traits and diseases.

Hekselman I, Yeger-Lotem E. Hekselman I, et al. Nat Rev Genet. 2020 Mar;21(3):137-150. doi: 10.1038/s41576-019-0200-9. Epub 2020 Jan 8. Nat Rev Genet. 2020. PMID: 31913361 Review.

6

Differential network analysis of multiple human tissue interactomes highlights tissue-selective processes and genetic disorder genes.

Basha O, Argov CM, Artzy R, Zoabi Y, Hekselman I, Alfandari L, Chalifa-Caspi V, Yeger-Lotem E. Basha O, et al. Among authors: hekselman i. Bioinformatics. 2020 May 1;36(9):2821-2828. doi: 10.1093/bioinformatics/btaa034. Bioinformatics. 2020. PMID: 31960892

7

Dosage-sensitive molecular mechanisms are associated with the tissue-specificity of traits and diseases.

Jubran J, Hekselman I, Novack L, Yeger-Lotem E. Jubran J, et al. Among authors: hekselman i. Comput Struct Biotechnol J. 2020 Nov 23;18:4024-4032. doi: 10.1016/j.csbj.2020.10.030. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 33363699 Free PMC article.

8

The differential activity of biological processes in tissues and cell subsets can illuminate disease-related processes and cell-type identities.

Sharon M, Vinogradov E, Argov CM, Lazarescu O, Zoabi Y, Hekselman I, Yeger-Lotem E. Sharon M, et al. Among authors: hekselman i. Bioinformatics. 2022 Mar 4;38(6):1584-1592. doi: 10.1093/bioinformatics/btab883. Bioinformatics. 2022. PMID: 35015838

9

The Organ-Disease Annotations (ODiseA) Database of Hereditary Diseases and Inflicted Tissues.

Hekselman I, Kerber L, Ziv M, Gruber G, Yeger-Lotem E. Hekselman I, et al. J Mol Biol. 2022 Jun 15;434(11):167619. doi: 10.1016/j.jmb.2022.167619. Epub 2022 Apr 30. J Mol Biol. 2022. PMID: 35504357

10

Predicting molecular mechanisms of hereditary diseases by using their tissue-selective manifestation.

Simonovsky E, Sharon M, Ziv M, Mauer O, Hekselman I, Jubran J, Vinogradov E, Argov CM, Basha O, Kerber L, Yogev Y, Segrè AV, Im HK; GTEx Consortium; Birk O, Rokach L, Yeger-Lotem E. Simonovsky E, et al. Among authors: hekselman i. Mol Syst Biol. 2023 Aug 8;19(8):e11407. doi: 10.15252/msb.202211407. Epub 2023 May 26. Mol Syst Biol. 2023. PMID: 37232043 Free PMC article.

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