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The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.
Chaikovsky AC, Li C, Jeng EE, Loebell S, Lee MC, Murray CW, Cheng R, Demeter J, Swaney DL, Chen SH, Newton BW, Johnson JR, Drainas AP, Shue YT, Seoane JA, Srinivasan P, He A, Yoshida A, Hipkins SQ, McCrea E, Poltorack CD, Krogan NJ, Diehl JA, Kong C, Jackson PK, Curtis C, Petrov DA, Bassik MC, Winslow MM, Sage J. Chaikovsky AC, et al. Among authors: diehl ja. Nature. 2021 Apr;592(7856):794-798. doi: 10.1038/s41586-021-03474-7. Epub 2021 Apr 14. Nature. 2021. PMID: 33854239 Free PMC article.
CDK4/6 inhibitor: from quiescence to senescence.
Yoshida A, Diehl JA. Yoshida A, et al. Among authors: diehl ja. Oncoscience. 2015 Oct 20;2(11):896-7. doi: 10.18632/oncoscience.256. eCollection 2015. Oncoscience. 2015. PMID: 26697514 Free PMC article. No abstract available.
MAPK Reliance via Acquired CDK4/6 Inhibitor Resistance in Cancer.
de Leeuw R, McNair C, Schiewer MJ, Neupane NP, Brand LJ, Augello MA, Li Z, Cheng LC, Yoshida A, Courtney SM, Hazard ES, Hardiman G, Hussain MH, Diehl JA, Drake JM, Kelly WK, Knudsen KE. de Leeuw R, et al. Among authors: diehl ja. Clin Cancer Res. 2018 Sep 1;24(17):4201-4214. doi: 10.1158/1078-0432.CCR-18-0410. Epub 2018 May 8. Clin Cancer Res. 2018. PMID: 29739788 Free PMC article.
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.
Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salas Salinas C, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, Fuchs SY, Diehl JA, Ruggero D, Koumenis C. Tameire F, et al. Among authors: diehl ja. Nat Cell Biol. 2019 Jul;21(7):889-899. doi: 10.1038/s41556-019-0347-9. Epub 2019 Jul 1. Nat Cell Biol. 2019. PMID: 31263264 Free PMC article.
SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors.
Yoshida A, Bu Y, Qie S, Wrangle J, Camp ER, Hazard ES, Hardiman G, de Leeuw R, Knudsen KE, Diehl JA. Yoshida A, et al. Among authors: diehl ja. Sci Adv. 2019 Sep 18;5(9):eaax6352. doi: 10.1126/sciadv.aax6352. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31555743 Free PMC article.
212 results