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Dynamic functional imaging of brain glucose utilization using fPET-FDG.
Villien M, Wey HY, Mandeville JB, Catana C, Polimeni JR, Sander CY, Zürcher NR, Chonde DB, Fowler JS, Rosen BR, Hooker JM. Villien M, et al. Among authors: wey hy. Neuroimage. 2014 Oct 15;100:192-9. doi: 10.1016/j.neuroimage.2014.06.025. Epub 2014 Jun 14. Neuroimage. 2014. PMID: 24936683 Free PMC article.
PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat.
Schroeder FA, Wang C, Van de Bittner GC, Neelamegam R, Takakura WR, Karunakaran A, Wey HY, Reis SA, Gale J, Zhang YL, Holson EB, Haggarty SJ, Hooker JM. Schroeder FA, et al. Among authors: wey hy. ACS Chem Neurosci. 2014 Oct 15;5(10):1055-62. doi: 10.1021/cn500162j. Epub 2014 Sep 19. ACS Chem Neurosci. 2014. PMID: 25188794 Free PMC article.
Insights into neuroepigenetics through human histone deacetylase PET imaging.
Wey HY, Gilbert TM, Zürcher NR, She A, Bhanot A, Taillon BD, Schroeder FA, Wang C, Haggarty SJ, Hooker JM. Wey HY, et al. Sci Transl Med. 2016 Aug 10;8(351):351ra106. doi: 10.1126/scitranslmed.aaf7551. Sci Transl Med. 2016. PMID: 27510902 Free PMC article. Clinical Trial.
Nasal neuron PET imaging quantifies neuron generation and degeneration.
Van de Bittner GC, Riley MM, Cao L, Ehses J, Herrick SP, Ricq EL, Wey HY, O'Neill MJ, Ahmed Z, Murray TK, Smith JE, Wang C, Schroeder FA, Albers MW, Hooker JM. Van de Bittner GC, et al. Among authors: wey hy. J Clin Invest. 2017 Feb 1;127(2):681-694. doi: 10.1172/JCI89162. Epub 2017 Jan 23. J Clin Invest. 2017. PMID: 28112682 Free PMC article.
PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia.
Gilbert TM, Zürcher NR, Wu CJ, Bhanot A, Hightower BG, Kim M, Albrecht DS, Wey HY, Schroeder FA, Rodriguez-Thompson A, Morin TM, Hart KL, Pellegrini AM, Riley MM, Wang C, Stufflebeam SM, Haggarty SJ, Holt DJ, Loggia ML, Perlis RH, Brown HE, Roffman JL, Hooker JM. Gilbert TM, et al. Among authors: wey hy. J Clin Invest. 2019 Jan 2;129(1):364-372. doi: 10.1172/JCI123743. Epub 2018 Dec 10. J Clin Invest. 2019. PMID: 30530989 Free PMC article. Clinical Trial.
68 results