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Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates.
Wallisch M, Lorentz CU, Lakshmanan HHS, Johnson J, Carris MR, Puy C, Gailani D, Hinds MT, McCarty OJT, Gruber A, Tucker EI. Wallisch M, et al. Among authors: gailani d. Res Pract Thromb Haemost. 2020 Feb 11;4(2):205-216. doi: 10.1002/rth2.12309. eCollection 2020 Feb. Res Pract Thromb Haemost. 2020. PMID: 32110750 Free PMC article.
Factor XII plays a pathogenic role in organ failure and death in baboons challenged with Staphylococcus aureus.
Silasi R, Keshari RS, Regmi G, Lupu C, Georgescu C, Simmons JH, Wallisch M, Kohs TCL, Shatzel JJ, Olson SR, Lorentz CU, Puy C, Tucker EI, Gailani D, Strickland S, Gruber A, McCarty OJT, Lupu F. Silasi R, et al. Among authors: gailani d. Blood. 2021 Jul 15;138(2):178-189. doi: 10.1182/blood.2020009345. Blood. 2021. PMID: 33598692 Free PMC article.
215 results