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CD40 Agonist Targeted to Fibroblast Activation Protein α Synergizes with Radiotherapy in Murine HPV-Positive Head and Neck Tumors.
Labiano S, Roh V, Godfroid C, Hiou-Feige A, Romero J, Sum E, Rapp M, Boivin G, Wyss T, Simon C, Bourhis J, Umaña P, Trumpfheller C, Tolstonog GV, Vozenin MC, Romero P. Labiano S, et al. Among authors: rapp m. Clin Cancer Res. 2021 Jul 15;27(14):4054-4065. doi: 10.1158/1078-0432.CCR-20-4717. Epub 2021 Apr 26. Clin Cancer Res. 2021. PMID: 33903200
Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity.
Sum E, Rapp M, Fröbel P, Le Clech M, Dürr H, Giusti AM, Perro M, Speziale D, Kunz L, Menietti E, Brünker P, Hopfer U, Lechmann M, Sobieniecki A, Appelt B, Adelfio R, Nicolini V, Freimoser-Grundschober A, Jordaan W, Labiano S, Weber F, Emrich T, Christen F, Essig B, Romero P, Trumpfheller C, Umaña P. Sum E, et al. Among authors: rapp m. Clin Cancer Res. 2021 Jul 15;27(14):4036-4053. doi: 10.1158/1078-0432.CCR-20-4001. Epub 2021 Mar 26. Clin Cancer Res. 2021. PMID: 33771854
CD103 is a hallmark of tumor-infiltrating regulatory T cells.
Anz D, Mueller W, Golic M, Kunz WG, Rapp M, Koelzer VH, Ellermeier J, Ellwart JW, Schnurr M, Bourquin C, Endres S. Anz D, et al. Among authors: rapp m. Int J Cancer. 2011 Nov 15;129(10):2417-26. doi: 10.1002/ijc.25902. Epub 2011 Apr 1. Int J Cancer. 2011. PMID: 21207371
CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes.
Rapp M, Wintergerst MWM, Kunz WG, Vetter VK, Knott MML, Lisowski D, Haubner S, Moder S, Thaler R, Eiber S, Meyer B, Röhrle N, Piseddu I, Grassmann S, Layritz P, Kühnemuth B, Stutte S, Bourquin C, von Andrian UH, Endres S, Anz D. Rapp M, et al. J Exp Med. 2019 May 6;216(5):1170-1181. doi: 10.1084/jem.20170277. Epub 2019 Mar 25. J Exp Med. 2019. PMID: 30910796 Free PMC article.
Cancer cell-derived IL-1α induces CCL22 and the recruitment of regulatory T cells.
Wiedemann GM, Knott MM, Vetter VK, Rapp M, Haubner S, Fesseler J, Kühnemuth B, Layritz P, Thaler R, Kruger S, Ormanns S, Mayr D, Endres S, Anz D. Wiedemann GM, et al. Among authors: rapp m. Oncoimmunology. 2016 Apr 25;5(9):e1175794. doi: 10.1080/2162402X.2016.1175794. eCollection 2016. Oncoimmunology. 2016. PMID: 27757295 Free PMC article.
835 results