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Sofalcone upregulates the nuclear factor (erythroid-derived 2)-like 2/heme oxygenase-1 pathway, reduces soluble fms-like tyrosine kinase-1, and quenches endothelial dysfunction: potential therapeutic for preeclampsia.
Onda K, Tong S, Nakahara A, Kondo M, Monchusho H, Hirano T, Kaitu'u-Lino T, Beard S, Binder N, Tuohey L, Brownfoot F, Hannan NJ. Onda K, et al. Among authors: tuohey l. Hypertension. 2015 Apr;65(4):855-62. doi: 10.1161/HYPERTENSIONAHA.114.04781. Epub 2015 Feb 9. Hypertension. 2015. PMID: 25667213
Heme Oxygenase-1 Is Not Decreased in Preeclamptic Placenta and Does Not Negatively Regulate Placental Soluble fms-Like Tyrosine Kinase-1 or Soluble Endoglin Secretion.
Tong S, Kaitu'u-Lino TJ, Onda K, Beard S, Hastie R, Binder NK, Cluver C, Tuohey L, Whitehead C, Brownfoot F, De Silva M, Hannan NJ. Tong S, et al. Among authors: tuohey l. Hypertension. 2015 Nov;66(5):1073-81. doi: 10.1161/HYPERTENSIONAHA.115.05847. Epub 2015 Aug 31. Hypertension. 2015. PMID: 26324507
Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction.
Brownfoot FC, Hastie R, Hannan NJ, Cannon P, Tuohey L, Parry LJ, Senadheera S, Illanes SE, Kaitu'u-Lino TJ, Tong S. Brownfoot FC, et al. Among authors: tuohey l. Am J Obstet Gynecol. 2016 Mar;214(3):356.e1-356.e15. doi: 10.1016/j.ajog.2015.12.019. Epub 2015 Dec 22. Am J Obstet Gynecol. 2016. PMID: 26721779
Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction.
Onda K, Tong S, Beard S, Binder N, Muto M, Senadheera SN, Parry L, Dilworth M, Renshall L, Brownfoot F, Hastie R, Tuohey L, Palmer K, Hirano T, Ikawa M, Kaitu'u-Lino T, Hannan NJ. Onda K, et al. Among authors: tuohey l. Hypertension. 2017 Mar;69(3):457-468. doi: 10.1161/HYPERTENSIONAHA.116.08408. Epub 2017 Jan 23. Hypertension. 2017. PMID: 28115513
Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction.
Brownfoot FC, Hannan NJ, Cannon P, Nguyen V, Hastie R, Parry LJ, Senadheera S, Tuohey L, Tong S, Kaitu'u-Lino TJ. Brownfoot FC, et al. Among authors: tuohey l. EBioMedicine. 2019 Mar;41:636-648. doi: 10.1016/j.ebiom.2019.02.013. Epub 2019 Feb 26. EBioMedicine. 2019. PMID: 30824385 Free PMC article.
27 results