Harris C - Search Results

1

DetectIS: a pipeline to rapidly detect exogenous DNA integration sites using DNA or RNA paired-end sequencing data.

Grassi L, Harris C, Zhu J, Hardman C, Hatton D. Grassi L, et al. Among authors: harris c. Bioinformatics. 2021 Nov 18;37(22):4230-4232. doi: 10.1093/bioinformatics/btab366. Bioinformatics. 2021. PMID: 33978747 Free PMC article.

2

Identification and characterization of an IgG sequence variant with an 11 kDa heavy chain C-terminal extension using a combination of mass spectrometry and high-throughput sequencing analysis.

Harris C, Xu W, Grassi L, Wang C, Markle A, Hardman C, Stevens R, Miro-Quesada G, Hatton D, Wang J. Harris C, et al. MAbs. 2019 Nov-Dec;11(8):1452-1463. doi: 10.1080/19420862.2019.1667740. Epub 2019 Oct 1. MAbs. 2019. PMID: 31570042 Free PMC article.

3

A platform for context-specific genetic engineering of recombinant protein production by CHO cells.

Cartwright JF, Arnall CL, Patel YD, Barber NOW, Lovelady CS, Rosignoli G, Harris CL, Dunn S, Field RP, Dean G, Daramola O, Gibson SJ, Peden AA, Brown AJ, Hatton D, James DC. Cartwright JF, et al. Among authors: harris cl. J Biotechnol. 2020 Mar 20;312:11-22. doi: 10.1016/j.jbiotec.2020.02.012. Epub 2020 Feb 27. J Biotechnol. 2020. PMID: 32114154

4

Targeted CHO cell engineering approaches can reduce HCP-related enzymatic degradation and improve mAb product quality.

Dovgan T, Golghalyani V, Zurlo F, Hatton D, Lindo V, Turner R, Harris C, Cui T. Dovgan T, et al. Among authors: harris c. Biotechnol Bioeng. 2021 Oct;118(10):3821-3831. doi: 10.1002/bit.27857. Epub 2021 Jun 29. Biotechnol Bioeng. 2021. PMID: 34125434

5

Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells.

Barzadd MM, Lundqvist M, Harris C, Malm M, Volk AL, Thalén N, Chotteau V, Grassi L, Smith A, Abadi ML, Lambiase G, Gibson S, Hatton D, Rockberg J. Barzadd MM, et al. Among authors: harris c. N Biotechnol. 2022 May 25;68:68-76. doi: 10.1016/j.nbt.2022.01.010. Epub 2022 Feb 2. N Biotechnol. 2022. PMID: 35123066 Free article.

6

Monoclonal Antibody Sequence Variants Disguised as Fragments: Identification, Characterization, and Their Removal by Purification Process Optimization.

Delmar JA, Harris C, Grassi L, Macapagal N, Wang J, Hatton D, Xu W. Delmar JA, et al. Among authors: harris c. J Pharm Sci. 2022 Nov;111(11):3009-3016. doi: 10.1016/j.xphs.2022.08.002. Epub 2022 Aug 5. J Pharm Sci. 2022. PMID: 35940243 Free article.

7

CHO synthetic promoters improve expression and product quality of biotherapeutic proteins.

Sou SN, Harris CL, Williams R, Kozub D, Zurlo F, Patel YD, Kallamvalli Illam Sankaran P, Daramola O, Brown A, James DC, Hatton D, Dunn S, Gibson SJ. Sou SN, et al. Among authors: harris cl. Biotechnol Prog. 2023 Sep-Oct;39(5):e3348. doi: 10.1002/btpr.3348. Epub 2023 Apr 28. Biotechnol Prog. 2023. PMID: 37114854

8

Interplay of heavy chain introns influences efficient transcript splicing and affects product quality of recombinant biotherapeutic antibodies from CHO cells.

Kelsall E, Harris C, Sen T, Hatton D, Dunn S, Gibson S. Kelsall E, et al. Among authors: harris c. MAbs. 2023 Jan-Dec;15(1):2242548. doi: 10.1080/19420862.2023.2242548. MAbs. 2023. PMID: 37555672 Free PMC article.

9

Identification and quantification of chain-pairing variants or mispaired species of asymmetric monovalent bispecific IgG1 monoclonal antibody format using reverse-phase polyphenyl chromatography coupled electrospray ionization mass spectrometry.

Poskute R, Sankaran PK, Sewell L, Lepore G, Shrubsall R, Dewis L, Watanabe Y, Wong V, Pascual Fernandez L, Mishra R, Holt A, Sou S, Harris C, Moreno Rodriguez C, Cankorur-Cetinkaya A, Smith J, Lonska N, Powell A, Cui T, Cheeks M, Lindo V. Poskute R, et al. Among authors: harris c. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Apr 15;1237:124085. doi: 10.1016/j.jchromb.2024.124085. Epub 2024 Mar 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2024. PMID: 38513430

10

Not Just an Oxymoron: The Utilitarian's Guide to Antimicrobial Stewardship in Transplant Infectious Diseases.

Gorsline CA, Sharma D, Harris CE, Hand J, Imlay H, Stohs EJ, So M, Kumar RN. Gorsline CA, et al. Among authors: harris ce. Transpl Infect Dis. 2024 Nov 25:e14399. doi: 10.1111/tid.14399. Online ahead of print. Transpl Infect Dis. 2024. PMID: 39584489

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