Huang SM - Search Results

1

3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration.

Wang H, Brown PC, Chow ECY, Ewart L, Ferguson SS, Fitzpatrick S, Freedman BS, Guo GL, Hedrich W, Heyward S, Hickman J, Isoherranen N, Li AP, Liu Q, Mumenthaler SM, Polli J, Proctor WR, Ribeiro A, Wang JY, Wange RL, Huang SM. Wang H, et al. Among authors: huang sm. Clin Transl Sci. 2021 Sep;14(5):1659-1680. doi: 10.1111/cts.13066. Epub 2021 Jun 16. Clin Transl Sci. 2021. PMID: 33982436 Free PMC article. Review.

2

Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).

Li Q, Guo D, Dong Z, Zhang W, Zhang L, Huang SM, Polli JE, Shu Y. Li Q, et al. Among authors: huang sm. Toxicol Appl Pharmacol. 2013 Nov 15;273(1):100-9. doi: 10.1016/j.taap.2013.08.024. Epub 2013 Aug 31. Toxicol Appl Pharmacol. 2013. PMID: 24001450 Free PMC article.

3

The role of bile salt export pump gene repression in drug-induced cholestatic liver toxicity.

Garzel B, Yang H, Zhang L, Huang SM, Polli JE, Wang H. Garzel B, et al. Among authors: huang sm. Drug Metab Dispos. 2014 Mar;42(3):318-22. doi: 10.1124/dmd.113.054189. Epub 2013 Dec 12. Drug Metab Dispos. 2014. PMID: 24335466 Free PMC article.

4

Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells.

Li D, Mackowiak B, Brayman TG, Mitchell M, Zhang L, Huang SM, Wang H. Li D, et al. Among authors: huang sm. Biochem Pharmacol. 2015 Nov 1;98(1):190-202. doi: 10.1016/j.bcp.2015.08.087. Epub 2015 Aug 12. Biochem Pharmacol. 2015. PMID: 26275810 Free PMC article.

5

Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells.

Li Z, Li D, Choi EY, Lapidus R, Zhang L, Huang SM, Shapiro P, Wang H. Li Z, et al. Among authors: huang sm. J Biol Chem. 2017 Aug 18;292(33):13890-13901. doi: 10.1074/jbc.M117.783860. Epub 2017 Jun 27. J Biol Chem. 2017. PMID: 28655760 Free PMC article.

6

Role of CYP3A in Oral Contraceptives Clearance.

Zhang N, Shon J, Kim MJ, Yu C, Zhang L, Huang SM, Lee L, Tran D, Li L. Zhang N, et al. Among authors: huang sm. Clin Transl Sci. 2018 May;11(3):251-260. doi: 10.1111/cts.12499. Epub 2017 Oct 6. Clin Transl Sci. 2018. PMID: 28986954 Free PMC article. Review. No abstract available.

7

Model-Informed Drug Development: Current US Regulatory Practice and Future Considerations.

Wang Y, Zhu H, Madabushi R, Liu Q, Huang SM, Zineh I. Wang Y, et al. Among authors: huang sm. Clin Pharmacol Ther. 2019 Apr;105(4):899-911. doi: 10.1002/cpt.1363. Epub 2019 Mar 1. Clin Pharmacol Ther. 2019. PMID: 30653670

8

Emerging Role of Organ-on-a-Chip Technologies in Quantitative Clinical Pharmacology Evaluation.

Isoherranen N, Madabushi R, Huang SM. Isoherranen N, et al. Among authors: huang sm. Clin Transl Sci. 2019 Mar;12(2):113-121. doi: 10.1111/cts.12627. Clin Transl Sci. 2019. PMID: 30740886 Free PMC article. Review.

9

Real-World Data and Clinical Pharmacology: A Regulatory Science Perspective.

Liu Q, Ramamoorthy A, Huang SM. Liu Q, et al. Among authors: huang sm. Clin Pharmacol Ther. 2019 Jul;106(1):67-71. doi: 10.1002/cpt.1413. Epub 2019 Apr 9. Clin Pharmacol Ther. 2019. PMID: 30964944 No abstract available.

10

A Change in Bile Flow: Looking Beyond Transporter Inhibition in the Development of Drug-induced Cholestasis.

Garzel B, Zhang L, Huang SM, Wang H. Garzel B, et al. Among authors: huang sm. Curr Drug Metab. 2019;20(8):621-632. doi: 10.2174/1389200220666190709170256. Curr Drug Metab. 2019. PMID: 31288715 Free PMC article. Review.

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