Bowles KM - Search Results

1

Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia.

Mistry JJ, Hellmich C, Lambert A, Moore JA, Jibril A, Collins A, Bowles KM, Rushworth SA. Mistry JJ, et al. Among authors: bowles km. Biomark Res. 2021 May 13;9(1):35. doi: 10.1186/s40364-021-00291-y. Biomark Res. 2021. PMID: 33985565 Free PMC article.

2

NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction.

Rushworth SA, Bowles KM, Raninga P, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Cancer Res. 2010 Apr 1;70(7):2973-83. doi: 10.1158/0008-5472.CAN-09-3407. Epub 2010 Mar 23. Cancer Res. 2010. PMID: 20332229

3

High basal nuclear levels of Nrf2 in acute myeloid leukemia reduces sensitivity to proteasome inhibitors.

Rushworth SA, Bowles KM, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Cancer Res. 2011 Mar 1;71(5):1999-2009. doi: 10.1158/0008-5472.CAN-10-3018. Epub 2011 Jan 6. Cancer Res. 2011. PMID: 21212410

4

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism.

Rushworth SA, Zaitseva L, Langa S, Bowles KM, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Oncotarget. 2010 Sep;1(5):359-366. doi: 10.18632/oncotarget.168. Oncotarget. 2010. PMID: 21307400 Free PMC article.

5

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1.

Heasman SA, Zaitseva L, Bowles KM, Rushworth SA, Macewan DJ. Heasman SA, et al. Among authors: bowles km. Oncotarget. 2011 Sep;2(9):658-68. doi: 10.18632/oncotarget.321. Oncotarget. 2011. PMID: 21911919 Free PMC article.

6

Bortezomib induces heme oxygenase-1 expression in multiple myeloma.

Barrera LN, Rushworth SA, Bowles KM, MacEwan DJ. Barrera LN, et al. Among authors: bowles km. Cell Cycle. 2012 Jun 15;11(12):2248-52. doi: 10.4161/cc.20343. Epub 2012 Jun 15. Cell Cycle. 2012. PMID: 22617388 Free PMC article.

7

BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB.

Rushworth SA, Bowles KM, Barrera LN, Murray MY, Zaitseva L, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Cell Signal. 2013 Jan;25(1):106-12. doi: 10.1016/j.cellsig.2012.09.008. Epub 2012 Sep 11. Cell Signal. 2013. PMID: 22975686

8

The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance.

Rushworth SA, Zaitseva L, Murray MY, Shah NM, Bowles KM, MacEwan DJ. Rushworth SA, et al. Among authors: bowles km. Blood. 2012 Dec 20;120(26):5188-98. doi: 10.1182/blood-2012-04-422121. Epub 2012 Oct 17. Blood. 2012. PMID: 23077289 Free article.

9

Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression.

Murray MY, Rushworth SA, Zaitseva L, Bowles KM, Macewan DJ. Murray MY, et al. Among authors: bowles km. Cell Cycle. 2013 Jul 1;12(13):2144-53. doi: 10.4161/cc.25251. Epub 2013 Jun 11. Cell Cycle. 2013. PMID: 23759586 Free PMC article.

10

Understanding the role of NRF2-regulated miRNAs in human malignancies.

Shah NM, Rushworth SA, Murray MY, Bowles KM, MacEwan DJ. Shah NM, et al. Among authors: bowles km. Oncotarget. 2013 Aug;4(8):1130-42. doi: 10.18632/oncotarget.1181. Oncotarget. 2013. PMID: 24029073 Free PMC article. Review.

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