Moore JA - Search Results

1

Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia.

Mistry JJ, Hellmich C, Lambert A, Moore JA, Jibril A, Collins A, Bowles KM, Rushworth SA. Mistry JJ, et al. Among authors: moore ja. Biomark Res. 2021 May 13;9(1):35. doi: 10.1186/s40364-021-00291-y. Biomark Res. 2021. PMID: 33985565 Free PMC article.

2

ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection.

Mistry JJ, Marlein CR, Moore JA, Hellmich C, Wojtowicz EE, Smith JGW, Macaulay I, Sun Y, Morfakis A, Patterson A, Horton RH, Divekar D, Morris CJ, Haestier A, Di Palma F, Beraza N, Bowles KM, Rushworth SA. Mistry JJ, et al. Among authors: moore ja. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24610-24619. doi: 10.1073/pnas.1913278116. Epub 2019 Nov 14. Proc Natl Acad Sci U S A. 2019. PMID: 31727843 Free PMC article.

3

Bone Marrow Senescence and the Microenvironment of Hematological Malignancies.

Hellmich C, Moore JA, Bowles KM, Rushworth SA. Hellmich C, et al. Among authors: moore ja. Front Oncol. 2020 Feb 25;10:230. doi: 10.3389/fonc.2020.00230. eCollection 2020. Front Oncol. 2020. PMID: 32161723 Free PMC article. Review.

4

Daratumumab inhibits acute myeloid leukaemia metabolic capacity by blocking mitochondrial transfer from mesenchymal stromal cells.

Mistry JJ, Moore JA, Kumar P, Marlein CR, Hellmich C, Pillinger G, Jibril A, Di Palma F, Collins A, Bowles KM, Rushworth SA. Mistry JJ, et al. Among authors: moore ja. Haematologica. 2021 Feb 1;106(2):589-592. doi: 10.3324/haematol.2019.242974. Haematologica. 2021. PMID: 32193250 Free PMC article. No abstract available.

5

Mitochondrial oxidative phosphorylation in cutaneous melanoma.

Kumar PR, Moore JA, Bowles KM, Rushworth SA, Moncrieff MD. Kumar PR, et al. Among authors: moore ja. Br J Cancer. 2021 Jan;124(1):115-123. doi: 10.1038/s41416-020-01159-y. Epub 2020 Nov 18. Br J Cancer. 2021. PMID: 33204029 Free PMC article. Review.

6

Mitochondria and the Tumour Microenvironment in Blood Cancer.

Moore JA, Mistry JJ, Rushworth SA. Moore JA, et al. Adv Exp Med Biol. 2021;1329:181-203. doi: 10.1007/978-3-030-73119-9_10. Adv Exp Med Biol. 2021. PMID: 34664240

7

Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection.

Mistry JJ, Hellmich C, Moore JA, Jibril A, Macaulay I, Moreno-Gonzalez M, Di Palma F, Beraza N, Bowles KM, Rushworth SA. Mistry JJ, et al. Among authors: moore ja. Nat Commun. 2021 Dec 8;12(1):7130. doi: 10.1038/s41467-021-27460-9. Nat Commun. 2021. PMID: 34880245 Free PMC article.

8

LC3-associated phagocytosis in bone marrow macrophages suppresses acute myeloid leukemia progression through STING activation.

Moore JA, Mistry JJ, Hellmich C, Horton RH, Wojtowicz EE, Jibril A, Jefferson M, Wileman T, Beraza N, Bowles KM, Rushworth SA. Moore JA, et al. J Clin Invest. 2022 Mar 1;132(5):e153157. doi: 10.1172/JCI153157. J Clin Invest. 2022. PMID: 34990402 Free PMC article.

9

Modelling Metabolic Shifts during Cardiomyocyte Differentiation, Iron Deficiency and Transferrin Rescue Using Human Pluripotent Stem Cells.

Johnson BB, Reinhold J, Holmes TL, Moore JA, Cowell V, Bernardo AS, Rushworth SA, Vassiliou V, Smith JGW. Johnson BB, et al. Among authors: moore ja. Metabolites. 2021 Dec 22;12(1):9. doi: 10.3390/metabo12010009. Metabolites. 2021. PMID: 35050131 Free PMC article.

10

PGC-1α induced mitochondrial biogenesis in stromal cells underpins mitochondrial transfer to melanoma.

Kumar PR, Saad M, Hellmich C, Mistry JJ, Moore JA, Conway S, Morris CJ, Bowles KM, Moncrieff MD, Rushworth SA. Kumar PR, et al. Among authors: moore ja. Br J Cancer. 2022 Jul;127(1):69-78. doi: 10.1038/s41416-022-01783-w. Epub 2022 Mar 26. Br J Cancer. 2022. PMID: 35347324 Free PMC article.

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