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The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR, Carr SA, Lindquist S, De Jager PL, Bartel DP, Myers CL, Greenamyre JT, Feany MB, Sunyaev SR, Chung CY, Khurana V. Hallacli E, et al. Among authors: sarkar s. Cell. 2022 Jun 9;185(12):2035-2056.e33. doi: 10.1016/j.cell.2022.05.008. Cell. 2022. PMID: 35688132 Free PMC article.
Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson's disease.
Sodders MJ, Avila-Pacheco J, Okorie EC, Shen M, Kumari N, Marathi A, Lakhani M, Bullock K, Pierce K, Dennis C, Jeanfavre S, Sarkar S, Scherzer CR, Clish C, Olsen AL. Sodders MJ, et al. Among authors: sarkar s. bioRxiv [Preprint]. 2024 Jun 2:2024.05.15.594309. doi: 10.1101/2024.05.15.594309. bioRxiv. 2024. PMID: 38798570 Free PMC article. Preprint.
Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.
Panicker N, Sarkar S, Harischandra DS, Neal M, Kam TI, Jin H, Saminathan H, Langley M, Charli A, Samidurai M, Rokad D, Ghaisas S, Pletnikova O, Dawson VL, Dawson TM, Anantharam V, Kanthasamy AG, Kanthasamy A. Panicker N, et al. Among authors: sarkar s. J Exp Med. 2019 Jun 3;216(6):1411-1430. doi: 10.1084/jem.20182191. Epub 2019 Apr 29. J Exp Med. 2019. PMID: 31036561 Free PMC article.
6,373 results