Shimazaki M - Search Results

1

Virtual clinical trial simulations for a novel KRAS^G12C inhibitor (ASP2453) in non-small cell lung cancer.

Sayama H, Marcantonio D, Nagashima T, Shimazaki M, Minematsu T, Apgar JF, Burke JM, Wille L, Nagasaka Y, Kirouac DC. Sayama H, et al. Among authors: shimazaki m. CPT Pharmacometrics Syst Pharmacol. 2021 Aug;10(8):864-877. doi: 10.1002/psp4.12661. Epub 2021 Jun 26. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34043291 Free PMC article.

2

Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.

Nakayama A, Nagashima T, Nishizono Y, Kuramoto K, Mori K, Homboh K, Yuri M, Shimazaki M. Nakayama A, et al. Among authors: shimazaki m. Br J Cancer. 2022 Mar;126(5):744-753. doi: 10.1038/s41416-021-01629-x. Epub 2021 Nov 18. Br J Cancer. 2022. PMID: 34795410 Free PMC article.

3

Discovery and biological evaluation of 1-{2,7-diazaspiro[3.5]nonan-2-yl}prop-2-en-1-one derivatives as covalent inhibitors of KRAS G12C with favorable metabolic stability and anti-tumor activity.

Imaizumi T, Akaiwa M, Abe T, Nigawara T, Koike T, Satake Y, Watanabe K, Kaneko O, Amano Y, Mori K, Yamanaka Y, Nagashima T, Shimazaki M, Kuramoto K. Imaizumi T, et al. Among authors: shimazaki m. Bioorg Med Chem. 2022 Oct 1;71:116949. doi: 10.1016/j.bmc.2022.116949. Epub 2022 Jul 30. Bioorg Med Chem. 2022. PMID: 35926326

4

Clinical activity of ASP8273 in Asian patients with non-small-cell lung cancer with EGFR activating and T790M mutations.

Murakami H, Nokihara H, Hayashi H, Seto T, Park K, Azuma K, Tsai CM, Yang JC, Nishio M, Kim SW, Kiura K, Inoue A, Takeda K, Kang JH, Nakagawa T, Takeda K, Akazawa R, Kaneko Y, Shimazaki M, Morita S, Fukuoka M, Nakagawa K. Murakami H, et al. Among authors: shimazaki m. Cancer Sci. 2018 Sep;109(9):2852-2862. doi: 10.1111/cas.13724. Epub 2018 Aug 9. Cancer Sci. 2018. PMID: 29972716 Free PMC article. Clinical Trial.

5

Reverse triiodothyronine nuclear binding in rat brain.

Kobayashi A, Shimazaki M, Hamada N, Morii H, Inoue A, Shimazu A. Kobayashi A, et al. Among authors: shimazaki m. Osaka City Med J. 1990 May;36(1):29-35. Osaka City Med J. 1990. PMID: 2385438

6

Studies on inhibition of adenosine deaminase by isocoformycin in vitro and in vivo.

Shimazaki M, Kumada Y, Takeuchi T, Umezawa H, Watanabe K. Shimazaki M, et al. J Antibiot (Tokyo). 1979 Jun;32(6):654-8. doi: 10.7164/antibiotics.32.654. J Antibiot (Tokyo). 1979. PMID: 468739 Free article.

7

Nuclear binding sites for reverse triiodothyronine in human placenta.

Kobayashi A, Shimazaki M, Kuwahara H, Ohashi H, Hashimoto R, Inoue A, Hamada N, Morii H, Shimazu A. Kobayashi A, et al. Among authors: shimazaki m. Osaka City Med J. 1989 Nov;35(2):137-44. Osaka City Med J. 1989. PMID: 2628841

8

Effects of reverse triiodothyronine on bone and calcium metabolism in rats.

Ohashi H, Shimazaki M, Hashimoto R, Kuwahara H, Kobayashi A, Shimazu A. Ohashi H, et al. Among authors: shimazaki m. Osaka City Med J. 1988 Oct;34(2):179-89. Osaka City Med J. 1988. PMID: 3237403 No abstract available.

9

Effects of thyroid hormone and actinomycin D on phosphate uptake of brush-border membrane vesicles from kidney of rachitic rats.

Kishida M, Umano T, Kadoya Y, Motoda T, Hashimoto R, Shimazaki M, Shimazu A. Kishida M, et al. Among authors: shimazaki m. Osaka City Med J. 1990 May;36(1):21-8. Osaka City Med J. 1990. PMID: 2385437

10

Ameliorating effects of thyroid hormone on rickets induced by a new rachitogenic diet.

Shimazaki M, Masuda H, Mitsuhashi T, Umano T, Chanoki Y, Kuwahara H, Sakai T, Shimazu A. Shimazaki M, et al. Osaka City Med J. 1985 Dec;31(2):83-91. Osaka City Med J. 1985. PMID: 3016633 No abstract available.

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