Medina MW - Search Results

1

Effect of SLCO1B1 T521C on Statin-Related Myotoxicity With Use of Lovastatin and Atorvastatin.

Lu B, Sun L, Seraydarian M, Hoffmann TJ, Medina MW, Risch N, Iribarren C, Krauss RM, Oni-Orisan A. Lu B, et al. Among authors: medina mw. Clin Pharmacol Ther. 2021 Sep;110(3):733-740. doi: 10.1002/cpt.2337. Epub 2021 Jul 23. Clin Pharmacol Ther. 2021. PMID: 34114646 Free PMC article.

2

Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment.

Krauss RM, Mangravite LM, Smith JD, Medina MW, Wang D, Guo X, Rieder MJ, Simon JA, Hulley SB, Waters D, Saad M, Williams PT, Taylor KD, Yang H, Nickerson DA, Rotter JI. Krauss RM, et al. Among authors: medina mw. Circulation. 2008 Mar 25;117(12):1537-44. doi: 10.1161/CIRCULATIONAHA.107.708388. Epub 2008 Mar 10. Circulation. 2008. PMID: 18332269

3

Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin.

Medina MW, Gao F, Ruan W, Rotter JI, Krauss RM. Medina MW, et al. Circulation. 2008 Jul 22;118(4):355-62. doi: 10.1161/CIRCULATIONAHA.108.773267. Epub 2008 Jun 16. Circulation. 2008. PMID: 18559695 Free PMC article.

4

The role of HMGCR alternative splicing in statin efficacy.

Medina MW, Krauss RM. Medina MW, et al. Trends Cardiovasc Med. 2009 Jul;19(5):173-7. doi: 10.1016/j.tcm.2009.10.003. Trends Cardiovasc Med. 2009. PMID: 20005478 Free PMC article. Review.

5

Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.

Mangravite LM, Medina MW, Cui J, Pressman S, Smith JD, Rieder MJ, Guo X, Nickerson DA, Rotter JI, Krauss RM. Mangravite LM, et al. Among authors: medina mw. Arterioscler Thromb Vasc Biol. 2010 Jul;30(7):1485-92. doi: 10.1161/ATVBAHA.110.203273. Epub 2010 Apr 22. Arterioscler Thromb Vasc Biol. 2010. PMID: 20413733 Free PMC article. Clinical Trial.

6

Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake.

Medina MW, Gao F, Naidoo D, Rudel LL, Temel RE, McDaniel AL, Marshall SM, Krauss RM. Medina MW, et al. PLoS One. 2011 Apr 29;6(4):e19420. doi: 10.1371/journal.pone.0019420. PLoS One. 2011. PMID: 21559365 Free PMC article.

7

RHOA is a modulator of the cholesterol-lowering effects of statin.

Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM. Medina MW, et al. PLoS Genet. 2012;8(11):e1003058. doi: 10.1371/journal.pgen.1003058. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166513 Free PMC article.

8

A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function.

Gao F, Ihn HE, Medina MW, Krauss RM. Gao F, et al. Among authors: medina mw. Hum Mol Genet. 2013 Apr 1;22(7):1424-31. doi: 10.1093/hmg/dds559. Epub 2013 Jan 7. Hum Mol Genet. 2013. PMID: 23297366 Free PMC article.

9

Alternative splicing in the regulation of cholesterol homeostasis.

Medina MW, Krauss RM. Medina MW, et al. Curr Opin Lipidol. 2013 Apr;24(2):147-52. doi: 10.1097/MOL.0b013e32835cf284. Curr Opin Lipidol. 2013. PMID: 23314925 Free PMC article. Review.

10

ATHENA: a tool for meta-dimensional analysis applied to genotypes and gene expression data to predict HDL cholesterol levels.

Holzinger ER, Dudek SM, Frase AT, Krauss RM, Medina MW, Ritchie MD. Holzinger ER, et al. Among authors: medina mw. Pac Symp Biocomput. 2013:385-96. Pac Symp Biocomput. 2013. PMID: 23424143 Free PMC article.

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