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Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition.
Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, Schmidt BZ, Raitano S, Van Den Bosch L, Nahmias Y, Cathomen T, Struys T, Verfaillie CM. Ordovás L, et al. Among authors: eggermont k. Stem Cell Reports. 2015 Nov 10;5(5):918-931. doi: 10.1016/j.stemcr.2015.09.004. Epub 2015 Oct 8. Stem Cell Reports. 2015. PMID: 26455413 Free PMC article.
Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.
García-León JA, Cabrera-Socorro A, Eggermont K, Swijsen A, Terryn J, Fazal R, Nami F, Ordovás L, Quiles A, Lluis F, Serneels L, Wierda K, Sierksma A, Kreir M, Pestana F, Van Damme P, De Strooper B, Thorrez L, Ebneth A, Verfaillie CM. García-León JA, et al. Among authors: eggermont k. Alzheimers Dement. 2018 Oct;14(10):1261-1280. doi: 10.1016/j.jalz.2018.05.007. Epub 2018 Jul 20. Alzheimers Dement. 2018. PMID: 30036493 Free article.
HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations.
Fazal R, Boeynaems S, Swijsen A, De Decker M, Fumagalli L, Moisse M, Vanneste J, Guo W, Boon R, Vercruysse T, Eggermont K, Swinnen B, Beckers J, Pakravan D, Vandoorne T, Vanden Berghe P, Verfaillie C, Van Den Bosch L, Van Damme P. Fazal R, et al. Among authors: eggermont k. EMBO J. 2021 Apr 1;40(7):e106177. doi: 10.15252/embj.2020106177. Epub 2021 Mar 10. EMBO J. 2021. PMID: 33694180 Free PMC article.
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy.
Imberechts D, Kinnart I, Wauters F, Terbeek J, Manders L, Wierda K, Eggermont K, Madeiro RF, Sue C, Verfaillie C, Vandenberghe W. Imberechts D, et al. Among authors: eggermont k. Brain. 2022 Dec 19;145(12):4368-4384. doi: 10.1093/brain/awac313. Brain. 2022. PMID: 36039535 Free PMC article.
Controlling and monitoring stem cell safety in vivo in an experimental rodent model.
Leten C, Roobrouck VD, Struys T, Burns TC, Dresselaers T, Vande Velde G, Santermans J, Lo Nigro A, Ibrahimi A, Gijsbers R, Eggermont K, Lambrichts I, Verfaillie CM, Himmelreich U. Leten C, et al. Among authors: eggermont k. Stem Cells. 2014 Nov;32(11):2833-44. doi: 10.1002/stem.1819. Stem Cells. 2014. PMID: 25142614
SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells.
García-León JA, Kumar M, Boon R, Chau D, One J, Wolfs E, Eggermont K, Berckmans P, Gunhanlar N, de Vrij F, Lendemeijer B, Pavie B, Corthout N, Kushner SA, Dávila JC, Lambrichts I, Hu WS, Verfaillie CM. García-León JA, et al. Among authors: eggermont k. Stem Cell Reports. 2018 Feb 13;10(2):655-672. doi: 10.1016/j.stemcr.2017.12.014. Epub 2018 Jan 11. Stem Cell Reports. 2018. PMID: 29337119 Free PMC article.
Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells.
García-León JA, García-Díaz B, Eggermont K, Cáceres-Palomo L, Neyrinck K, Madeiro da Costa R, Dávila JC, Baron-Van Evercooren A, Gutiérrez A, Verfaillie CM. García-León JA, et al. Among authors: eggermont k. Nat Protoc. 2020 Nov;15(11):3716-3744. doi: 10.1038/s41596-020-0395-4. Epub 2020 Oct 23. Nat Protoc. 2020. PMID: 33097924
44 results