Nichols AEC - Search Results

1

Impact of isolation method on cellular activation and presence of specific tendon cell subpopulations during in vitro culture.

Nichols AEC, Muscat SN, Miller SE, Green LJ, Richards MS, Loiselle AE. Nichols AEC, et al. FASEB J. 2021 Jul;35(7):e21733. doi: 10.1096/fj.202100405R. FASEB J. 2021. PMID: 34160846 Free PMC article.

2

The cellular basis of fibrotic tendon healing: challenges and opportunities.

Nichols AEC, Best KT, Loiselle AE. Nichols AEC, et al. Transl Res. 2019 Jul;209:156-168. doi: 10.1016/j.trsl.2019.02.002. Epub 2019 Feb 8. Transl Res. 2019. PMID: 30776336 Free PMC article. Review.

3

Cell non-autonomous functions of S100a4 drive fibrotic tendon healing.

Ackerman JE, Nichols AE, Studentsova V, Best KT, Knapp E, Loiselle AE. Ackerman JE, et al. Elife. 2019 May 24;8:e45342. doi: 10.7554/eLife.45342. Elife. 2019. PMID: 31124787 Free PMC article.

4

Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing.

Nichols AEC, Oh I, Loiselle AE. Nichols AEC, et al. J Orthop Res. 2020 Jan;38(1):13-22. doi: 10.1002/jor.24388. Epub 2019 Jun 24. J Orthop Res. 2020. PMID: 31166037 Free PMC article. Review.

5

Effects of tamoxifen on tendon homeostasis and healing: Considerations for the use of tamoxifen-inducible mouse models.

Best KT, Studentsova V, Ackerman JE, Nichols AEC, Myers M, Cobb J, Knapp E, Awad HA, Loiselle AE. Best KT, et al. Among authors: nichols aec. J Orthop Res. 2021 Jul;39(7):1572-1580. doi: 10.1002/jor.24767. Epub 2020 Jun 9. J Orthop Res. 2021. PMID: 32485026 Free PMC article.

6

NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival.

Best KT, Nichols AEC, Knapp E, Hammert WC, Ketonis C, Jonason JH, Awad HA, Loiselle AE. Best KT, et al. Among authors: nichols aec. Sci Signal. 2020 Nov 17;13(658):eabb7209. doi: 10.1126/scisignal.abb7209. Sci Signal. 2020. PMID: 33203721 Free PMC article.

7

Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis.

Best KT, Korcari A, Mora KE, Nichols AE, Muscat SN, Knapp E, Buckley MR, Loiselle AE. Best KT, et al. Elife. 2021 Jan 22;10:e62203. doi: 10.7554/eLife.62203. Elife. 2021. PMID: 33480357 Free PMC article.

8

CCR2 is expressed by tendon resident macrophage and T cells, while CCR2 deficiency impairs tendon healing via blunted involvement of tendon-resident and circulating monocytes/macrophages.

Muscat S, Nichols AEC, Gira E, Loiselle AE. Muscat S, et al. Among authors: nichols aec. FASEB J. 2022 Nov;36(11):e22607. doi: 10.1096/fj.202201162R. FASEB J. 2022. PMID: 36250393 Free PMC article.

9

Defining the spatial-molecular map of fibrotic tendon healing and the drivers of Scleraxis-lineage cell fate and function.

Ackerman JE, Best KT, Muscat SN, Pritchett EM, Nichols AEC, Wu CL, Loiselle AE. Ackerman JE, et al. Among authors: nichols aec. Cell Rep. 2022 Nov 22;41(8):111706. doi: 10.1016/j.celrep.2022.111706. Cell Rep. 2022. PMID: 36417854 Free PMC article.

10

Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype.

Korcari A, Nichols AEC, Buckley MR, Loiselle AE. Korcari A, et al. Among authors: nichols aec. Elife. 2023 Jan 19;12:e84194. doi: 10.7554/eLife.84194. Elife. 2023. PMID: 36656751 Free PMC article.

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