Schiefner A - Search Results

1

Molecular recognition of structurally disordered Pro/Ala-rich sequences (PAS) by antibodies involves an Ala residue at the hot spot of the epitope.

Schilz J, Binder U, Friedrich L, Gebauer M, Lutz C, Schlapschy M, Schiefner A, Skerra A. Schilz J, et al. Among authors: schiefner a. J Mol Biol. 2021 Sep 3;433(18):167113. doi: 10.1016/j.jmb.2021.167113. Epub 2021 Jun 20. J Mol Biol. 2021. PMID: 34161780 Free article.

2

Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin.

Gebauer M, Schiefner A, Matschiner G, Skerra A. Gebauer M, et al. Among authors: schiefner a. J Mol Biol. 2013 Feb 22;425(4):780-802. doi: 10.1016/j.jmb.2012.12.004. Epub 2012 Dec 10. J Mol Biol. 2013. PMID: 23238252

3

Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen.

Schiefner A, Gebauer M, Richter A, Skerra A. Schiefner A, et al. Structure. 2018 Apr 3;26(4):649-656.e3. doi: 10.1016/j.str.2018.02.003. Epub 2018 Mar 8. Structure. 2018. PMID: 29526433 Free article.

4

Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization.

Schiefner A, Walser R, Gebauer M, Skerra A. Schiefner A, et al. Acta Crystallogr F Struct Biol Commun. 2020 Jul 1;76(Pt 7):320-325. doi: 10.1107/S2053230X20008328. Epub 2020 Jul 1. Acta Crystallogr F Struct Biol Commun. 2020. PMID: 32627748 Free PMC article.

5

A disulfide-free single-domain V(L) intrabody with blocking activity towards huntingtin reveals a novel mode of epitope recognition.

Schiefner A, Chatwell L, Körner J, Neumaier I, Colby DW, Volkmer R, Wittrup KD, Skerra A. Schiefner A, et al. J Mol Biol. 2011 Dec 2;414(3):337-55. doi: 10.1016/j.jmb.2011.09.034. Epub 2011 Sep 24. J Mol Biol. 2011. PMID: 21968397

6

Extra-domain B in oncofetal fibronectin structurally promotes fibrillar head-to-tail dimerization of extracellular matrix protein.

Schiefner A, Gebauer M, Skerra A. Schiefner A, et al. J Biol Chem. 2012 May 18;287(21):17578-17588. doi: 10.1074/jbc.M111.303131. Epub 2012 Mar 22. J Biol Chem. 2012. PMID: 22442152 Free PMC article.

7

The menagerie of human lipocalins: a natural protein scaffold for molecular recognition of physiological compounds.

Schiefner A, Skerra A. Schiefner A, et al. Acc Chem Res. 2015 Apr 21;48(4):976-85. doi: 10.1021/ar5003973. Epub 2015 Mar 10. Acc Chem Res. 2015. PMID: 25756749 Review.

8

Structural differences between the ectodomains of murine and human CD98hc.

Deuschle FC, Schiefner A, Skerra A. Deuschle FC, et al. Among authors: schiefner a. Proteins. 2019 Aug;87(8):693-698. doi: 10.1002/prot.25686. Epub 2019 Apr 23. Proteins. 2019. PMID: 30958588

9

Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice.

Deuschle FC, Schiefner A, Brandt C, Skerra A. Deuschle FC, et al. Among authors: schiefner a. Protein Sci. 2020 Aug;29(8):1774-1783. doi: 10.1002/pro.3894. Epub 2020 Jun 16. Protein Sci. 2020. PMID: 32463547 Free PMC article.

10

The dimeric crystal structure of the human fertility lipocalin glycodelin reveals a protein scaffold for the presentation of complex glycans.

Schiefner A, Rodewald F, Neumaier I, Skerra A. Schiefner A, et al. Biochem J. 2015 Feb 15;466(1):95-104. doi: 10.1042/BJ20141003. Biochem J. 2015. PMID: 25422905

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